Curcumin-related hybrid compounds as potential antimalarial agents : design, synthesis, mechanistic investigations, biological evaluation and pharmacokinetic studies by Guantai, Eric

Other Authors: “…Chibale, Kelly…”
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The application of the Multi-Component Reaction (MCR) strategy in the design and synthesis of new antiplasmodial and antimycobacterial agents by Tukulula, Matshawandile

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Synthesis of activity-based protein profiling probes for malaria and hypertension disease models & potential novel ACE inhibitors with an attenuated zinc binding group by Kambafwile, Henry Kunda

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Antimalarial and cysteine protease inhibitor pharmacophores as scaffolds for new antimalarial agents by Musonda, Chitalu Christopher

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Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping by Njuguna, Nicholas M

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In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid by Njoroge, Mathew

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Synthesis, antimalarial evaluation, Ç-hematin inhibition, and in silico and in vitro ADMET profiling of 4-aminoquinoline-hydroxypyridinone hybrids by Andayi, Warren Andrew

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Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery by Kigondu, Elizabeth Victoria Mumbi

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Design, synthesis and biological evaluation of verapamil analogues, reversed isoniazids and hybrid efflux pump inhibitors against Mycobacterium tuberculosis by Kumar, Malkeet

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Synthesis, pharmacological and solubility evaluation of antiplasmodial pyrido[1,2-a]benzimidazoles with cyclic and functionalized amine side chain substituents by Ndubi, Ferdinand Wafula

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A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria by Kaur, Gurminder

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Synthesis, structure-activity relationship and solubility profiling of antimycobacterial aminoquinazolinones by Akester, Jessica Nicole

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Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents by Omollo, Charles

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Development of N-domain selective Angiotensin-I Converting Enzyme (ACE) inhibitors using Computer Aided Drug Discovery (CADD) by Fienberg, Stephen

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Antimycobacterial 2-aminoquinazolinones and benzoxazole-based oximes: synthesis, biological evaluation, physicochemical profiling and supramolecular derivatization by Njaria, Paul Magutu

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Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles by Barnard, Linley Nicole

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Semi-synthesis and evaluation of fusidic acid derivatives as potential antituberculosis agents by Shanika, Petrus Siningu

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Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity by Wasuna, Antonina

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Preclinical pharmacokinetic evaluation of novel antimalarial and antituberculosis drug leads by Strydom, Natasha

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Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles by Mayoka, Godfrey Wabwile

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