Construction of an Effector–Target Interaction Network for Identification of Immune‐Related Effectors in Ralstonia pseudosolanacearum

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Investigation of HIV-TB co-infection through analysis of the potential impact of host genetic variation on host-pathogen protein interactions by Heekes, Alexa Storme

“…We generated a host-pathogen functional interaction network made up of inter- and intraspecies protein interactions, gene expression during co-infection, drug-target interactions, and human genetic variation. Differential expression and network centrality properties were used to prioritise proteins that may be important in co-infection. …”
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Copper Oxide Nanoparticles as Delivery Vehicles for Different Pt (II)-Drugs: Experimental and Theoretical Evaluation by Abdelkareem, Shahdan

“…These challenges arise in part from the drugs’ susceptibility to premature hydrolysis, off-target interactions in the bloodstream, and degradation in the gastrointestinal tract, which collectively limit their ability to reach and act on tumor cells. …”
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An Activity-Based Proteomics Approach for Identifying Ajoene's S-thiolation Protein Targets in Blood and Cancer Cells by Kusza, Daniel Andreas

“…Subsequent biological validation studies confirmed that the probe retained cytotoxicity against cancer cell lines in vitro (human epithelial mammary gland adenocarcinoma cancer cells (MDA-MB-231) and WHCO1) and shared the same compound–target interaction as its parent ajoene; namely, the regioselective S-thiolation of cellular proteins. …”
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In silico and in vitro inhibition of α- glucosidase and α-amylase by compounds from culinary herbs and spices, for possible treatment of type 2 diabetes

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The potential antidiabetic properties of purple tea [Camellia sinensis (L.) O Kuntze], purple tea ellagitannins, and urolithins

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An integrative data-analysis of miRNA-related contributions to the pathophysiology of neuropsychiatric disorders by Prinsloo, Hendrik Johannes

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