Homology-based in silico identification of putative protein-ligand interactions in the malaria parasite

Get full text

Discovery and genomic architecture of Cercospora zeina (Crous & U. Braun) effector genes

Get full text

Synthesis of novel Tetrahydroisoquinoline-related estrogen receptor modulators by Mabank, Tanya

Get full text

In-silico guided design, synthesis and bio-evaluation of potential chemotherapeutic agents against malaria, cancer and disease-causing pathogens

Get full text

Development of N-domain selective Angiotensin-I Converting Enzyme (ACE) inhibitors using Computer Aided Drug Discovery (CADD) by Fienberg, Stephen

“…Three computer aided drug discovery (CADD) approaches were pursued to design N-domain selective drug-like ACE inhibitors (ACEi) with an acidic P₂ functional group that would confer N-domain selectivity via an interaction with Arg381 in the S₂ subsite. …”
Get full text

Leveraging shotgun proteomics for optimised interpretation of data-independent acquisition data: identification of diagnostic biomarkers for paediatric tuberculosis by Ehlers, Ashley

Get full text

Non-Neuroleptic Antitubercular and Anticancer Therapeutics through Rational Drug Remodelling of Phenothiazines and Related Antipsychotics by Semenya, Manare Molahlegi Dorothy

“…In light of shrinking pharmaceutical drug pipelines and drug resistance, innovative drug discovery strategies are of imperative need. Drug repurposing and related strategies such as drug rescue and drug remodelling have garnered significant research interest. …”
Get full text

A journey of mixed-race identity development within the South African context : an autoethnography

Get full text

The fundamental role of spectral scattering in the ocean colour Phytoplankton Functional Type signal by Robertson Lain, Elisabeth

“…This is a new modelling capability, and its application in case studies and sensitivity analyses has resulted in improved understanding of the PFT/assemblage-related signal, in particular the discovery that phytoplankton spectral scattering is the primary driver of the PFT-related signal. …”
Get full text

Antibiotics from Streptomyces spp. isolated from Namibian desert sand

Get full text

Functional genomics and systems genetics of cellulose biosynthesis in Eucalyptus

Get full text

The diversity of polyketides in the South Atlantic and Southern Ocean

Get full text

Ecklonia maxima: a potential NRF2 antioxidant modulator in Glucotoxicity-induced oxidative stress by Bekko, Adam

Get full text

Investigating teaching and learning support for students with hearing impairment at a university in the Western Cape by Bell, Diane

Get full text

An investigation into the anti-obesity properties of Cyclopia by Jack, Babalwa Unice

Get full text

Genetic diversity of Anaplasma marginale in cattle and in putative novel Anaplasma species from wildlife in Mpumalanga, South Africa

Get full text

Unravelling the mystery of the shark genus Mustelus in southern Africa using a multidisciplinary approach by Maduna, Simo Njabulo

Get full text

Status of the invasive wasp species, Vespula germanica and Polistes dominula in South Africa, and the feasibility of various management strategies by Van Zyl, Carolina

Get full text

Evaluation of host biosignatures for targeted screening for tuberculosis at the point of care, and monitoring of the response to TB treatment by Mutavhatsindi, Hygon

Get full text