Development and optimisation of pre-treatment procedures to enhance total haemoglobin for carboxyhaemoglobin analysis in diluted blood samples by Dos Reis, Domonica-Jean

“…The purpose of this study was to assess and optimise two pre-treatment procedures to effectively increase tHb in excessively dilute blood samples, thereby enabling the determination of COHb using CO-oximetry. …”
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In-house genotypic antiretroviral resistance test : optimisation and validation for use in research and diagnostics by Claassen, Mathilda

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Assessing inter-method agreement of drug-based phenotyping metrics between dried blood spot and plasma sampling

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Characterisation of Plasmodium falciparum proteins expressed on infected red blood cell surfaces as potential drug targets for severe malaria therapy

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Experimental investigation of the viability of using nano-bubbles for intravascular oxygenation by Smit, Mynhardt

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The detection of Mycobacterium avium subsp. paratuberculosis in sheep in the Western Cape, South Africa by Howell, Shannon Kimlynn

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Effects of conventional versus rumen protected fat on growth performance and carcass characteristics of feedlot bulls fed Zilpaterol diets

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The role of underdiagnosed viruses in neonatal sepsis by Mahlangu, Tshegofatso Perseverance

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Assessing type 2 diabetes associated NeuroCognitive impairment using an e-screening tool in a South African population by Bobrow, Kirsten

“…Validating this tool for this patient population and optimising its role in routine clinical care need further study.…”
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Assessing cardiotonic steroids involvement in hypertensive rat models with Helicobacter pylori infections

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Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles by Mayoka, Godfrey Wabwile

“…In this thesis, further structural diversity around the PBI motif 3 (Figure 1) was pursued with the aim of generating analogues for structure-activity and structure-property relationship studies. Beyond the asexual blood stage activity, the library of compounds generated was also evaluated for activity against the liver and gametocyte stages of Plasmodium. …”
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Effect of 12 weeks fish supplementation of an enhanced usual diet on cognition of resource limited independently living elderly in a retirement village : a randomised controlled tr...

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Exercise, stress and immune system functional responses by Smith, Carine

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An investigation into the cellular mechanisms underlying photodynamic rejuvenation in human skin by Van Kets, Victoria Louise

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Coaxially electrospun heparin-eluting scaffolds for vascular graft application by Krause, Gerhard Jaco

“…Coaxially incorporated HepNa+ also exhibited initial burst release (67.5-69.7 %, 3 days) for both the low and high heparin content groups followed by improved sustained release (81.9 - 97.7%, 6 weeks). …”
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Gestational diabetes self-management and remote monitoring mobile platform by Collier, Jason

“…The results of the investigation informed the design of low-fidelity and high-fidelity mock-ups of the platform. …”
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Anti-diabetic activity of extracts and a bioactive compound isolated from Hypoxis hemerocallidea (Hypoxidaceae) in a murine model of spontaneous diabetes

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The relationship between the insecticide dichloro-diphenyl-trichloroethane and chloroquine in Plasmodium falciparum resistance by Makowa, Hazel Beverly

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Substance P radiolabeled with 68Ga as a novel-imaging agent for increased Neurokinin-1 Receptor availability in chronic pain disorders

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A Simple Virus Recovery Assay to detect the Replication-Competent HIV-1 Reservoir in Children by Van Zyl, Carli

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