Effects of 25-hydroxyvitamin D3 on cell growth and cell death via regulation of the vitamin D metabolising system in a cervical adenocarcinoma cell line

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Molecular regulation of autophagy and metastasis in breast cancer: new insights into the role of serum amyloid A by Du Plessis, Manisha

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The role of seminal plasma in the regulation of inflammation and inflammatory pathways in the cervix: potential for cervical cancer progression and HIV transmission in South Africa... by Adefuye, Anthonio Oladele

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Systems level cancer disease target identification using tumor microenvironment dynamics by Makinde, Funmilayo Lydia

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In vitro study of in silico designed sirtuin 1 and bromodomain 4 inhibitors on human neuroblastoma SH-SY5Y and acute myeloid leukemia U937 cells

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Evaluation of a strategy based on multi-drug targeting of cancer proteins in breast cancer cell lines

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An investigation of the impact of the B cell lymphoma factor Activation Induced Cytidine Deaminase (AICDA/AID) on epigenetic plasticity by Makofane, Lincon Kgasha

“…To address this burden, it is crucial to deepen our understanding of the biology of the disease to create opportunities for addressing therapeutic challenges. Epigenetic regulation has recently emerged as a prominent factor in cancer progression, and aberrant epigenetic alterations have been reported in many key cancer-driving genes. …”
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Progestins and breast cancer : significance of progesterone receptor isoforms and their altered ratios by Cartwright, Meghan Carni

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Phytoestrogenic extracts of Cyclopia modulate molecular targets involved in the prevention and treatment of breast cancer by Visser, Jacobus Albertus Koch

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An investigation into the role of TBX3 in breast carcinogenesis and its regulation by the TGF-?1 signalling pathway by Li, Jarod Ang

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Cofactor of BRCA1 as a modulator of hepatocellular carcinoma growth and migration by El Zeneini, Eman Mahmoud

“…In the field of cancer, the role of COBRA1 is not yet fully understood. …”
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The c-Myc/TBX3/nucleolin/Hsc70 signalling axis in breast cancer by Ncube, Stephanie Maria

“…While haploinsufficiency of TBX3 results in ulnar mammary syndrome, its overexpression is linked to several cancers. We and others have shown that TBX3 drives tumour formation, invasion and metastasis of several sarcoma subtypes as well as melanoma, cervical cancer and breast cancer. …”
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Investigating a novel small molecule inhibitor of nuclear import as an anti-cancer approach by Chi, Ru-pin Alicia

“…An in silico screen for Kpnβ1 inhibitors identified several small molecules that showed inhibitory effects on nuclear import as well as cancer killing activity. In this study, we aimed to examine the potential of one such small molecule, the Inhibitor of Nuclear Import-43 (INI-43) as a lead compound with anti-cancer activities using multiple cancer models. …”
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The relationship between HIF-1α and autophagy activity in the hypoxic environment of breast cancer by Mills, Justin

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An Activity-Based Proteomics Approach for Identifying Ajoene's S-thiolation Protein Targets in Blood and Cancer Cells by Kusza, Daniel Andreas

“…Importantly, we have validated that ajoene S-thioallylates glutathione S-transferase (GSTP1), which is a known cancer-therapy target in breast cancer. Overall, this study complements findings on the cancer-cell protein targets of allicin from crushed garlic, by identifying proteins regulating apoptotic and antiproliferative signalling pathways. …”
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Characterization of the promoter region of the HAMP gene implicated in iron metabolism and its possible association with Oesophageal cancer in the black South African population by McGregor, Nathaniel Wade

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Potential anticancer actions of cholecalciferol on a cervical squamous carcinoma cell line

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A comparative analysis of the G1/S transition control in kinetic models of the eukaryotic cell cycle by Conradie, Riaan

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Investigation of vasculogenic mimicry in melanoma tissue

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The role of Lymphoblastic leukemia 1 (Lyl1) in Mycobacterium tuberculosis (Mtb) infection by Jones, Shelby-Sara Ann

“…Since its discovery in 1989, many reports have been published describing its relationship with cancer as well as demonstrating its function during hematopoiesis. …”
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