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NEXT-scASV: a Nextflow pipeline for allele-specific variant calling from single-cell RNA-seq data
Published in GigaScience (2026)Get full text
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The barrier functions of the cervical mucus plugs and purified mucins against a panel of HIV-1 strains in the contexts of cell-free and cell-to-cell infections
Published 2019“…Our laboratory found that the cervical mucins—but not the crude cervical mucus plugs—isolated and purified from the mucus plugs inhibit HIV-1 infection in an in vitro cell-free inhibition assay. We aimed to characterize and compare the inhibition of cell-free and cell-associated HIV-1 strains by the crude cervical mucus plugs and purified cervical mucins. …”
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The chromatin landscape of colorectal cancer cells
Published 2021“…Differential CTCF enrichment analysis between the peaks in primary sigmoidal colon cells and CRC cell lines is then conducted using DeSeq2 within DiffBind. …”
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Eragrostis nindensis: unravelling senescence in an African desiccation tolerant grass
Published 2020“…Research has been conducted into a unique group of plants, called “resurrection plants”, that can withstand up to 95% tissue water-loss without compromising viability by, inter alia, undergoing extensive metabolic reprogramming and suppressing senescence. …”
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The functional analysis of XhLEA3-2 - a LEA_4 from the resurrection plant, Xerophyta humilis
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Evaluation of southern African maize germplasm for phytoalexin accumulation following inoculation by Fusarium verticillioides
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Evolution of the ZRS and the Regulation of SHH Expression in the Forelimbs of Bats.
Published 2024Get full text
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Biomolecular condensation of intrinsically disordered regions in P. falciparum and H. sapiens transcription factors
Published 2023“…The study these of so-called transcriptional condensates has so far not addressed the role of the general transcription factors (GTFs) and has not investigated the phenomenon in non-model eukaryotes such as P. falciparum. …”
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Development of plant-produced African horse sickness vaccines
Published 2021“…In the second part of the study, the use of the so-called SpyTag/SpyCatcher or bacterial “superglue” technology was investigated. …”
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Label-free proteomic analysis of Xerophyta schlechteri leaf tissue under dehydration stress
Published 2021“…Most higher plants cannot withstand severe water loss, except for a small group of angiosperms called resurrection plants. They can survive severe water loss without the loss of viability by employing mechanisms that aid them in desiccation tolerance. …”
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Design of a high intensity ultrasound dispersion cell
Published 2015Get full text
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The modelling of granular flow using the particle-in-cell method
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Differential effects of TNfα on satellite cell differentiation
Published 2012Get full text
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Single stage boost inverter for standalone fuel cell applications
Published 2017“…The proton exchange membrane fuel cell (PEMFC) is a promising technology that can be manufactured in South Africa because of the platinum catalyst required. …”
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Genomics of sickle cell disease and fetal hemoglobin in African populations
Published 2025“…Background More than 300,000 babies are born with sickle cell disease (SCD) each year. About 79% of these births occurs in sub-Saharan Africa where the sickle variant is known to have originated in the genetic background of the ancestors of Agriculturalist populations. …”
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The failure of radio to communicate knowledge of sickle cell disorder in N igeria
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Investigating the effects of enhanced catecholamine stimulation in stem cell-derived cardiomyocytes
Published 2026“…Methods: Pluripotent mouse embryonic stem cells were differentiated, in vitro, into pulsatile cardiomyocyte-like cells via the formation of cell clusters called embryoid bodies (EBs). …”
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Fibroblast growth factors, A potential game plan for regeneration of skeletal muscle
Published 2019Get full text
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