PEGylated chitosan / doxorubicin nanoparticles and conjugated with monoclonal antibodies for breast cancer therapy by Zidan, Omar Helmi

“…This functionalization has the potential of evading systemic side effects of parenteral free DOX and promoting cancerous endocytosis through receptor mediated interaction. In-vitro cytotoxicity effects of PEGylated DOX loaded CSNP, free DOX, Anti-HER2 PEGylated DOX loaded CSNP and Anti-hMAM PEGylated DOX loaded CSNP were tested against breast cancer cell line (MCF7) and normal fibroblast cell line (L929). …”
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Establishment of recombinant antibody technologies allowing for the generation of SNAP-tag fusion proteins by Nundalall, Trishana

“…Specific monoclonal antibodies (mAbs) and derivatives thereof, have already been established as a revolutionary tool for drug delivery to cancerous cells. Such antibodies have been conjugated to cytotoxic drugs to form antibody-drug conjugates, which may exhibit multiple advantages over their unconjugated counterparts, but their general use in clinical application has been restricted due to developmental deliberations. …”
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Design and synthesis of Covalent Kinase Inhibitors Utilising Novel Electrophiles by Hodson, Luke Eric

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Evaluation of a strategy based on multi-drug targeting of cancer proteins in breast cancer cell lines

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Characterisation, health-promoting properties and food applications of anthocyanin-rich pigments of flowers from the Geraniaceae and Lamiaceae plant families

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South Africa's security relations with the Mercosur countries

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Self-effektiwiteit en MIV/VIGS-voorkomende gedrag by 'n groep hoërskoolleerlinge by Esterhuyse, E. A. (Elizabeth Aletta)

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Investigation of Mycobacterium tuberculosis protein expression and analysis of humoral immune responses of TB patients by Pheiffer, Carmen

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