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Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells
Published 2014Get full text
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Regulation of sodium channel densities in A6 renal epithelial cells by hormonally-dependent mechanisms
Published 2023“…Epithelial sodium channels (ENaC) located in the apical membranes of transporting epithelia, such as cells of the renal distal nephron, constitute the rate limiting step in the transcellular transport of sodium. …”
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In vitro culture of Boer goat mammary epithelial cells to form a monolayer constituting a tight barrier to drug movement
Published 2016Get full text
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The role of surfactant in, and a comparison of, the permeability of porcine and human epithelia to various chemical compounds
Published 2008Get full text
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MiR-590-3p suppresses cellular migration and clonogenicity and epithelial to mesenchymal transition in the HepG2 cell line by targeting MDM2 and SETD7
Published 2020“…In our study, the expression levels of miR-590-3p, as well as its function in HCC, were examined in two different HCC cell lines: HepG2 and SNU449 that represent an early and advanced stage of HCC, respectively. …”
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Effects of cadmium chromium and mercury alone and in combination of lung tussue of Sprague-Dawley rats
Published 2019Get full text
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Relative level of glucocorticoid and progesterone receptor: implications for immune and reproductive functions in women
Published 2025“…The widespread expression of GR across different FGT cells, including epithelial, stromal and specific T lymphocytes as well as systemic T lymphocytes and monocytes, signifies its diverse roles throughout the body. …”
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Investigation of the role of the DNA-modifying enzyme, activation-induced cytidine deaminase (AID), in cancer
Published 2016“…The function of AID in the oncogenic process is not well defined and therefore this project is aimed at using cell culture models to study the function of AID in cancer. …”
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Determining the impact of Heligmosomoides polygyrus infection on the development of colitis
Published 2020“…Currently, established literature emphasises the protective role of helminth infection in mouse models of inflammatory bowel disease (IBD). Utilising two well-established murine models of human disease, the oxazolone and dextran sulfate sodium (DSS) models, I found that induction of murine IBD is highly sensitive to diet change and mouse gender. …”
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Modulating ADAM-10 activity and expression in cervical and oesophageal cancer cells
Published 2017“…Drug treatment also resulted in an increase in cellular adhesion as well as a significant decrease in the invasion and migration of WHC05 and HeLa cells. …”
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An investigation into the role of TBX3 in breast carcinogenesis and its regulation by the TGF-?1 signalling pathway
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In silico redesign and de novo design of anti-MUC1 monoclonal antibodies
Published 2024“…Mucin 1 (MUC1) is a cellular membrane-tethered protein which is abnormally glycosylated and overexpressed in several epithelial cancers. This abnormal glycosylation is hypothesized to participate in the hyper-activation of signaling pathways which promote tumor growth and provides a suitable target for detection and treatment of epithelial cancers via antibodies. …”
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Characterizing various aspects of the male genital tract barrier function and immunity
Published 2025“…Furthermore, it is not well understood why there remains a group of circumcised males who remain susceptible to infection. …”
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