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  1. Investigating role of IL-4 receptor alpha (IL-4Ra) in murine models of atopic dermatitis by Scibiorek, Martyna

    Published 2023
    “…We investigated the importance of interleukin 4 receptor alpha (IL- 4Rα) signalling specifically on B and T cells to understand the requirement of this signalling axis in epicutaneous skin sensitisation during AD. We investigated 3 models of AD using House dust mite (HDM), Ovalbumin (OVA) and low-calcemic analog of vitamin D (MC903) on mouse strains lacking IL-4Ra on various B and T cells. …”
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    Thesis
  2. Investigating the role of sestrin 1 and sestrin 2 in preclinical models of tuberculosis disease by Naidoo, Saiyukthi

    Published 2026
    “…By generating Sesn2 and macrophage-specific Sesn1 knockout mouse models, we uncovered the role of these genes for the first time in inflammation and TB disease. …”
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    Thesis
  3. The role of Cysteinyl leukotriene receptor-1 during experimental helminth infections in murine model by Mosala, Paballo Pertunia

    Published 2021
    “…In conclusion, the current study demonstrated both positive and negative roles for cysLTs signaling through cysLTR1 during different helminth infection models. Absence of cysLTR1 during N. brasiliensis leads to delayed expulsion of adult worms and impaired recall of memory responses, indicating that cysteinyl leukotriene signaling via cysLTR1 is essential for orchestrating host protective responses. …”
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    Thesis
  4. Comparative immune-profiling of three cattle breeds infested with Rhipicephalus microplus and Ixodes ricinus-infested BALB/c mice

    Published 2019
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    Thesis
  5. Prolonged tuberculosis-associated immune reconstitution inflammatory syndrome: characteristics and risk factors by Bana, Tasnim Mohammed

    Published 2016
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    Thesis
  6. Characterization of tuberculous lesions in naturally infected African buffalo (Syncerus caffer) by Laisse, Claudio Joao Mourao

    Published 2010
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    Thesis
  7. Investigating the role of IL-4Rα mediated signalling on Foxp3⁺ T regulatory cells during cutaneous leishmaniasis by Maine, Rebeng

    Published 2021
    “…To investigate this further, a novel BALB/c model was utilized in which the IL-4Rα chain was conditionally knocked out on Treg cells (Foxp3ᶜʳᵉIL-4Rα⁻<sup>/</sup>ˡᵒˣ mice). …”
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    Thesis
  8. The role of Interleukin-4 induced gene 1 (IL-4i1) in allergic asthma and atopic dermatitis by Ngomti, Amkele

    Published 2023
    “…In both disease models, we saw a significant reduction in total IgE in IL-4i1- deficient mice compared to IL-4i1+/+ littermate controls. …”
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    Thesis
  9. Influence of helminth infection on vaginal immunity by Omondi, Fidilia

    Published 2023
    “…We then investigated the impact of primary helminth infection on B and T cell immunity in the female reproductive tract using the mouse model of hookworm infection, Nippostrongylus brasiliensis. …”
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    Thesis
  10. Regulation of HPV infection and cervical cancer development following a helminth infection by Butters, Claire

    Published 2025
    “…These results were then validated in vivo, through the development of a physiological murine model for HPV infec7on, u7lising a luminescent HPV PsV and in vivo imaging system (IVIS). …”
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    Thesis
  11. Clinical signs, lesions and viral antigen distribution in alpacas (Vicugna pacos) naturally infected with Rift Valley fever virus

    Published 2024
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    Thesis
  12. Bronchoscopic assessment and management of children presenting with clinically significant airway obstruction due to tuberculosis by Goussard, Pierre

    Published 2015
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    Thesis
  13. Feature detection in ultrasound images for computer aided diagnosis of Hodgkin's Lymphoma by Dawood, Tareen

    Published 2022
    “…A support vector machine model was built, with two experiments performed to evaluate the model. …”
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    Thesis
  14. The characterisation of dendritic cell, microglial, macrophage and T cell responses during mycobacterial infection of the central nervous system by Kgoadi, Khanyisile

    Published 2022
    “…Conclusion: We successfully reproduced the CNS-TB murine model, which proved valuable in studying immune responses. …”
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    Thesis
  15. Invasive carcinoma of the cervix in young women : a controlled study (1974-1983) including re-examination of the histology and cytology for evidence of human papillomavirus infecti... by Jennings, O G N

    Published 2017
    “…Multivariate analysis with a proportional hazards general linear model was performed for simultaneous control of confounding factors. …”
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    Thesis