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Investigating role of IL-4 receptor alpha (IL-4Ra) in murine models of atopic dermatitis
Published 2023“…We analysed cellular infiltrate in the skin and inguinal lymph nodes (LN) by flow cytometry, histology of the skin, serum antibodies and cytokines by ELISA. …”
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Investigating the role of sestrin 1 and sestrin 2 in preclinical models of tuberculosis disease
Published 2026“…The increased inflammation was associated with enhanced total lung and lymph node cells, immune cell recruitment and lung tissue pathology. …”
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The role of Cysteinyl leukotriene receptor-1 during experimental helminth infections in murine model
Published 2021“…Additionally, cysLTR1-/- mice exhibited impaired production of IL-13 in the lungs and draining lymph nodes compared with wildtype mice. Finally, there was reduced recruitment of effector CD4+ T cells and central memory CD4+ T cells in the lungs of cysLTR1 deficient mice compared to control mice. …”
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Prolonged tuberculosis-associated immune reconstitution inflammatory syndrome: characteristics and risk factors
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Comparative immune-profiling of three cattle breeds infested with Rhipicephalus microplus and Ixodes ricinus-infested BALB/c mice
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Investigating the role of IL-4Rα mediated signalling on Foxp3⁺ T regulatory cells during cutaneous leishmaniasis
Published 2021“…In a murine model of Leishmania major infection, susceptible BALB/c mice develop a detrimental Type 2 immune response characterized by the production of interleukin (IL)-4 and IL-13, which single through a common receptor, the IL-4 receptor alpha chain (IL-4Rα). …”
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Characterization of tuberculous lesions in naturally infected African buffalo (Syncerus caffer)
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The role of Interleukin-4 induced gene 1 (IL-4i1) in allergic asthma and atopic dermatitis
Published 2023“…In both disease models, we saw a significant reduction in total IgE in IL-4i1- deficient mice compared to IL-4i1+/+ littermate controls. …”
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Influence of helminth infection on vaginal immunity
Published 2023“…We then investigated the impact of primary helminth infection on B and T cell immunity in the female reproductive tract using the mouse model of hookworm infection, Nippostrongylus brasiliensis. …”
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Regulation of HPV infection and cervical cancer development following a helminth infection
Published 2025“…This was associated with a significant increase in eosinophil accumula7on in the female genital tract (FGT) and iliac lymph node (iLN), the draining lymph node of the FGT. …”
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Feature detection in ultrasound images for computer aided diagnosis of Hodgkin's Lymphoma
Published 2022“…A support vector machine model was built, with two experiments performed to evaluate the model. …”
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The characterisation of dendritic cell, microglial, macrophage and T cell responses during mycobacterial infection of the central nervous system
Published 2022“…The histopathological results showed the successful reproduction of the murine CNS-TB infection model. For immunophenotyping, flow cytometry analysis of single-cell suspensions generated from brains and cervical lymph nodes were characterized for phenotypic and functional profiles. …”
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Invasive carcinoma of the cervix in young women : a controlled study (1974-1983) including re-examination of the histology and cytology for evidence of human papillomavirus infecti...
Published 2017“…Multivariate analysis with a proportional hazards general linear model was performed for simultaneous control of confounding factors. …”
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Bronchoscopic assessment and management of children presenting with clinically significant airway obstruction due to tuberculosis
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Chronic stress-associated accelerated ageing: inflammation and oxidative stress treatment
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Proteogenomics of the Spotted Hyena (Crocuta crocuta)
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Investigating the molecular pathogenesis of tuberculosis-associated immune reconstitution inflammatory syndrome
Published 2025“…TB-IRIS is characterized by hyperinflammation and tissue damage. Pulmonary and lymph node involvement are the most common clinical manifestations. …”
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