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Improving pruning wound protection against grapevine trunk disease pathogens
Published 2014Get full text
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Development of a Dusky kob scFv gene phage display library for the discovery of antibodies to Brome mosaic virus - a proxy for a novel, emerging fish pathogen
Published 2022“…Consequently, antibodies expressed by a diverse repertoire of genes coding for the single chain variable fragment (scFv) of immunoglobulin M can be isolated and screened for affinity to a specific infectious agent or parasite. …”
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Investigating maize inbred line responses following infection by the Mycotoxigenic fungus Fusarium verticilliodes
Published 2016Get full text
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Identifying Genes and Novel Variants Involved in Nonsyndromic Hearing Impairment, and Assessment of the Psychosocial Burden of Hearing Impairment in Cameroon
Published 2022“…NSHI is the most frequent clinical entity and accounts for 86.1% to 92.5% of cases of hereditary HI in the Cameroonian population. No pathogenic variant was described in GJB6 gene, and the prevalence of pathogenic variants in GJB2 ranged from 0% to 0.5%. …”
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Molecular and evolutionary analysis of a gene conserved in most Orthopoxviruses
Published 2017“…This was tested by interruption of the E5R gene in vaccinia virus; this did not affect the ability of the virus to form plaques in cell culture, but appeared to reduce the pathogenicity of the 'virus for rabbits. The deduced amino acid sequences were analysed for conserved and variable regions within the gene, to which no specific function has yet been assigned.…”
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Differential proteomic profiling towards elucidation of TB-IRIS pathogenesis
Published 2022“…Proteomic data were additionally analysed to detect Mtb proteins, preliminarily analyse variable post-translational modifications (PTMs) of interest, and identify candidate prognostic and diagnostic biomarkers. …”
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Functional Genome-wide Association Studies (fGWAS) and genomics landscape of signatures of polygenic adaptation in Botswana populations with HIV-1 C infection
Published 2023“…Based on functional predictions, it was assigned to a non-coding transcript exon of the MT-RNR2 gene's 16S ribosomal RNA (rRNA), and it was regarded as having potential pathogenicity. …”
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