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Predictors of diffuse myocardial fibrosis in HIV infected persons: A multiparametric cardiovascular magnetic resonance study
Published 2020“…Our hypothesis was that ART would be associated with regression of myocardial fibrosis in HIV. Myocardial fibrosis is associated with an unfavourable outcome in many different clinical settings. …”
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Investigating cerebrovascular pressure reactivity in a large cohort of children with severe traumatic brain injury
Published 2022“…Given the differences between adult and paediatric TBI pathophysiology, CA needs examination in a larger cohort of paediatric TBI. …”
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The risk and severity of preeclampsia secondary to iodine deficiency and iodine deficiency-mediated subclinical hypothyroidism: mechanisms and early cardiovascular consequences
Published 2022“…Possible mechanisms in the pathophysiology of preeclampsia associated with iodine deficiency, resultant thyroid dysfunction and other nutritional or inflammatory factors Using data of normotensive and preeclamptic women from Kinshasa Province, Democratic Republic of Congo, we have characterised four main pathophysiological pathways through which low iodine intake in pregnancy may predispose to preeclampsia. …”
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Risk factors associated with blood pressure variation in sickle cell disease in Cameroon
Published 2025“…Herein, we investigated (clinical, genetic, and epidemiological) risk factors associated with RSH or Systemic Hypertension in SCD patients in Cameroon to gain insight into the pathophysiology of BP variation in this disease in an African setting. …”
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Autophagy and antipsychotic treatment response: Characterising a potential relationship in a neuropsychiatric disorders context
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Pharmacogenomics of sickle cell disease therapeutics: pain and drug metabolism associated gene variants and hydroxyurea-induced post-transcriptional expression of miRNAs
Published 2022“…For association studies, statistical models using regression frameworks to analyse 40 variants were performed in R®. …”
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Temporal changes in the cardiometabolic disease risk profile of the Bellville south mixed-ancestry community between 2008/09 AND 2014/16
Published 2022“…Linear and logistic regression analyses adjusted for year of study, age, and gender, were applied for all three studies. …”
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