Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Elucidation of bipolar disorder : a convergent approach using genetics and imaging
The aims were to determine whether variants, within ten selected candidate genes, have an association with BPD and whether any relationship exists between these variants and brain imaging volumes in subjects with BPD. The objectives were to i) select a list of BPD candidate genes, ii) identify a coh...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Human Genetics
2014
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613340137684992 |
|---|---|
| access_status_str | Open Access |
| author | Dalvie, Shareefa |
| author2 | Ramesar, Rajkumar S |
| author_browse | Dalvie, Shareefa Ramesar, Rajkumar S |
| author_facet | Ramesar, Rajkumar S Dalvie, Shareefa |
| author_sort | Dalvie, Shareefa |
| collection | Thesis |
| description | The aims were to determine whether variants, within ten selected candidate genes, have an association with BPD and whether any relationship exists between these variants and brain imaging volumes in subjects with BPD. The objectives were to i) select a list of BPD candidate genes, ii) identify a cohort of individuals from the BPD registry, iii) genotype the candidate genes using a polymerase chain reaction (PCR) based technology, iv) analyse the genotyping data with the appropriate statistical methods, and v) obtain brain imaging data and perform the appropriate statistical analysis. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10371 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:33.896Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Human Genetics |
| publisherStr | Division of Human Genetics |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10371 Elucidation of bipolar disorder : a convergent approach using genetics and imaging Dalvie, Shareefa Ramesar, Rajkumar S Medicine The aims were to determine whether variants, within ten selected candidate genes, have an association with BPD and whether any relationship exists between these variants and brain imaging volumes in subjects with BPD. The objectives were to i) select a list of BPD candidate genes, ii) identify a cohort of individuals from the BPD registry, iii) genotype the candidate genes using a polymerase chain reaction (PCR) based technology, iv) analyse the genotyping data with the appropriate statistical methods, and v) obtain brain imaging data and perform the appropriate statistical analysis. 2014-12-28T14:54:08Z 2014-12-28T14:54:08Z 2011 Master Thesis Masters MSc http://hdl.handle.net/11427/10371 eng application/pdf Division of Human Genetics Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Dalvie, Shareefa Elucidation of bipolar disorder : a convergent approach using genetics and imaging |
| thesis_degree_str | Master's |
| title | Elucidation of bipolar disorder : a convergent approach using genetics and imaging |
| title_full | Elucidation of bipolar disorder : a convergent approach using genetics and imaging |
| title_fullStr | Elucidation of bipolar disorder : a convergent approach using genetics and imaging |
| title_full_unstemmed | Elucidation of bipolar disorder : a convergent approach using genetics and imaging |
| title_short | Elucidation of bipolar disorder : a convergent approach using genetics and imaging |
| title_sort | elucidation of bipolar disorder a convergent approach using genetics and imaging |
| topic | Medicine |
| url | http://hdl.handle.net/11427/10371 |
| work_keys_str_mv | AT dalvieshareefa elucidationofbipolardisorderaconvergentapproachusinggeneticsandimaging |