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Includes bibliography.
| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Surgery
2014
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| _version_ | 1867613882708656128 |
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| access_status_str | Open Access |
| author | Radebold, Klaus |
| author2 | Bornman, PC |
| author_browse | Bornman, PC Radebold, Klaus |
| author_facet | Bornman, PC Radebold, Klaus |
| author_sort | Radebold, Klaus |
| collection | Thesis |
| description | Includes bibliography. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10762 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:43:12.903Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Surgery |
| publisherStr | Department of Surgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10762 Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome Radebold, Klaus Bornman, PC Surgery Includes bibliography. Despite major advances over the last two decades with the management of patients with Zollinger-Ellison syndrome (ZES), unanswered questions remain concerning the natural history of the disease, the impact of new diagnostics modalities on cure rates, and the role of surgery in the era of modem medical therapies. The aims of the thesis are to (i) analyse the database of 40 ZES patients treated at Groote Schuur Hospital (GSH) over two decades, with special reference to the impact of various surgical strategies on outcome, (ii) investigate a possible correlation between biological tissue marker expression and tumour behaviour, (iii) study the effect of somatostatin receptor scintigraphy (SRS) on surgical cure rates, and (iv) assess the efficacy and safety of a new proton pump inhibitor (pantoprazole) in controlling acid hypersecretion. 2014-12-31T19:54:34Z 2014-12-31T19:54:34Z 2000 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/10762 eng application/pdf Department of Surgery Faculty of Health Sciences University of Cape Town |
| spellingShingle | Surgery Radebold, Klaus Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome |
| thesis_degree_str | Doctoral |
| title | Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome |
| title_full | Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome |
| title_fullStr | Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome |
| title_full_unstemmed | Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome |
| title_short | Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome |
| title_sort | evaluation of new diagnostic and treatment strategies in the management of the zollinger ellison syndrome |
| topic | Surgery |
| url | http://hdl.handle.net/11427/10762 |
| work_keys_str_mv | AT radeboldklaus evaluationofnewdiagnosticandtreatmentstrategiesinthemanagementofthezollingerellisonsyndrome |