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Cellular immunity of naïve and BCG vaccinated neonates
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2015
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| _version_ | 1867614177889091584 |
|---|---|
| access_status_str | Open Access |
| author | Watkins, Marcia Linda Vivienne |
| author2 | Kaplan, Gilla |
| author_browse | Kaplan, Gilla Watkins, Marcia Linda Vivienne |
| author_facet | Kaplan, Gilla Watkins, Marcia Linda Vivienne |
| author_sort | Watkins, Marcia Linda Vivienne |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10984 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:47:54.408Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10984 Cellular immunity of naïve and BCG vaccinated neonates Watkins, Marcia Linda Vivienne Kaplan, Gilla Medicine Includes abstract. Includes bibliographical references (leaves 153-187). Despite more than 95% vaccination coverage with Mycobacterium bovis Bacille Calmette-Guérin (BCG), tuberculosis (TB) remains epidemic in South Africa. The dichotomy that successful pregnancy is usually associated with a type 2 (Th2) cytokine profile in the newborn child, whereas immunity to Mycobacterium tuberculosis (Mtb) is associated with the development of a type 1 helper (Th1) cytokine response, could impact on the subsequent adaptive immune response to BCG vaccination. Previous studies have suggested that immune responses in early life may be defective and related to the immaturity of antigen-presenting cells and/or T cells. 2015-01-02T09:16:34Z 2015-01-02T09:16:34Z 2010 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/10984 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Watkins, Marcia Linda Vivienne Cellular immunity of naïve and BCG vaccinated neonates |
| thesis_degree_str | Doctoral |
| title | Cellular immunity of naïve and BCG vaccinated neonates |
| title_full | Cellular immunity of naïve and BCG vaccinated neonates |
| title_fullStr | Cellular immunity of naïve and BCG vaccinated neonates |
| title_full_unstemmed | Cellular immunity of naïve and BCG vaccinated neonates |
| title_short | Cellular immunity of naïve and BCG vaccinated neonates |
| title_sort | cellular immunity of naive and bcg vaccinated neonates |
| topic | Medicine |
| url | http://hdl.handle.net/11427/10984 |
| work_keys_str_mv | AT watkinsmarcialindavivienne cellularimmunityofnaiveandbcgvaccinatedneonates |