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Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Psychiatry and Mental Health
2015
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| _version_ | 1867613357151879168 |
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| access_status_str | Open Access |
| author | Joska, John Anton |
| author2 | Flisher, Alan J |
| author_browse | Flisher, Alan J Joska, John Anton |
| author_facet | Flisher, Alan J Joska, John Anton |
| author_sort | Joska, John Anton |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/11363 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:51.693Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Psychiatry and Mental Health |
| publisherStr | Department of Psychiatry and Mental Health |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/11363 Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape Joska, John Anton Flisher, Alan J Stein, Dan J Psychiatry Includes abstract. Includes bibliographical references. HIV-associated neurocognitive disorders (HAND) remain prevalent in the era of highly active anti-retroviral therapy (HAART). The aim of the study was to investigate whether HAND are as prevalent in South Africa as in other regions, and whether individuals with HAND in South Africa will respond to HAART. The literature was reviewed to elucidate potential mechanisms of the development of HIV-associated dementia (HAD), the most severe form of HAND, and to establish the effect that HAART has exerted on HAND across diverse studies. A prospective clinical cohort study was initiated in Cape Town, comprising 170 participants. The reviewed literature suggests that HAD is likely mediated by a range of HIV-related factors (including possible difference in HIV sub-type) and host-related factors. 2015-01-05T06:59:42Z 2015-01-05T06:59:42Z 2010 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/11363 eng application/pdf Department of Psychiatry and Mental Health Faculty of Health Sciences University of Cape Town |
| spellingShingle | Psychiatry Joska, John Anton Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape |
| thesis_degree_str | Doctoral |
| title | Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape |
| title_full | Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape |
| title_fullStr | Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape |
| title_full_unstemmed | Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape |
| title_short | Neurocognitive disorders in young adults commencing highly active anti-retroviral treatment in the Western Cape |
| title_sort | neurocognitive disorders in young adults commencing highly active anti retroviral treatment in the western cape |
| topic | Psychiatry |
| url | http://hdl.handle.net/11427/11363 |
| work_keys_str_mv | AT joskajohnanton neurocognitivedisordersinyoungadultscommencinghighlyactiveantiretroviraltreatmentinthewesterncape |