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HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Neurosurgery
2015
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| _version_ | 1867613169369743361 |
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| access_status_str | Open Access |
| author | Cross, Helen Margot |
| author2 | Combrinck, MI |
| author_browse | Combrinck, MI Cross, Helen Margot |
| author_facet | Combrinck, MI Cross, Helen Margot |
| author_sort | Cross, Helen Margot |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/11759 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:52.071Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Neurosurgery |
| publisherStr | Division of Neurosurgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/11759 HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy Cross, Helen Margot Combrinck, MI Neuroscience Includes bibliographical references. This study aimed to determine whether highly active antiretroviral therapy (HAART) improved cognitive function in HIV positive people in South Africa, and whether this effect differed according to the CNS penetration-effectiveness (CPE) of the regimen used. I also investigated potential HIV-Associated Neurocognitive Disorders (HAND) biomarkers (serum neopterin, osteopontin and neurofilament H) to determine their relationship to the severity of cognitive impairment at baseline in HAART-naïve patients, and whether initial levels of these biomarkers related to the change in cognitive function a year later. 2015-01-08T19:51:16Z 2015-01-08T19:51:16Z 2012 Master Thesis Masters MMed http://hdl.handle.net/11427/11759 eng application/pdf Division of Neurosurgery Faculty of Health Sciences University of Cape Town |
| spellingShingle | Neuroscience Cross, Helen Margot HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy |
| thesis_degree_str | Master's |
| title | HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy |
| title_full | HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy |
| title_fullStr | HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy |
| title_full_unstemmed | HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy |
| title_short | HIV-associated neurocognitive disorders biomarkers and the response to antiretroviral therapy |
| title_sort | hiv associated neurocognitive disorders biomarkers and the response to antiretroviral therapy |
| topic | Neuroscience |
| url | http://hdl.handle.net/11427/11759 |
| work_keys_str_mv | AT crosshelenmargot hivassociatedneurocognitivedisordersbiomarkersandtheresponsetoantiretroviraltherapy |