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In silico investigation of the mechanism of ricin-catalysed depurination reaction and design of novel ricin inhibitors
Ricin is a dimeric enzyme found in the castor bean plant. It is extremely toxic with a fatal dose for humans ranging from 0.1-1.0 ug/kg. This has lead to its use as a biological weapon. Cell death is caused when ricin ceases the protein synthesis by removing a specific adenine (A-4324) of the GAGA t...
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| Language: | English |
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Department of Chemistry
2015
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