Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
L-arginine overproduction in Corynebacterium glutamicum ATCC 13032
Includes abstract.
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Molecular and Cell Biology
2015
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613174396616704 |
|---|---|
| access_status_str | Open Access |
| author | Theron, Grant de V |
| author2 | Reid, Sharon J |
| author_browse | Reid, Sharon J Theron, Grant de V |
| author_facet | Reid, Sharon J Theron, Grant de V |
| author_sort | Theron, Grant de V |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12122 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:56.645Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12122 L-arginine overproduction in Corynebacterium glutamicum ATCC 13032 Theron, Grant de V Reid, Sharon J Cell Biology Includes abstract. Includes bibliographical references (p. 155-174). Corynebacterium glutamicum is widely used for the commercial production of a variety of amino acids, including L-lysine, L-glutamate and L-threonine. With the exception of Larginine, the biosynthesis and regulation of most of these compounds in this bacterium are relatively well characterised in the literature. The research presented here focuses on improving our understanding of the regulation of L-arginine biosynthesis in C. glutamicum. This was performed with the ultimate goal of creating strains capable of producing L-arginine commercially. A novel gene replacement system was initially used for the directed mutation of the Larginine biosynthetic gene cluster in C. glutamicum ATCC 13032. This was met with limited success, however, and the pK19mobsacB vector was thus adopted for further mutagenesis of this region. 2015-01-13T03:59:24Z 2015-01-13T03:59:24Z 2009 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/12122 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Cell Biology Theron, Grant de V L-arginine overproduction in Corynebacterium glutamicum ATCC 13032 |
| thesis_degree_str | Doctoral |
| title | L-arginine overproduction in Corynebacterium glutamicum ATCC 13032 |
| title_full | L-arginine overproduction in Corynebacterium glutamicum ATCC 13032 |
| title_fullStr | L-arginine overproduction in Corynebacterium glutamicum ATCC 13032 |
| title_full_unstemmed | L-arginine overproduction in Corynebacterium glutamicum ATCC 13032 |
| title_short | L-arginine overproduction in Corynebacterium glutamicum ATCC 13032 |
| title_sort | l arginine overproduction in corynebacterium glutamicum atcc 13032 |
| topic | Cell Biology |
| url | http://hdl.handle.net/11427/12122 |
| work_keys_str_mv | AT therongrantdev larginineoverproductionincorynebacteriumglutamicumatcc13032 |