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Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa
Includes bibliographical references (leaves 114-147).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Virology
2015
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| _version_ | 1867613715648479232 |
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| access_status_str | Open Access |
| author | Zembe, Lycias |
| author2 | Burgers, Wendy |
| author_browse | Burgers, Wendy Zembe, Lycias |
| author_facet | Burgers, Wendy Zembe, Lycias |
| author_sort | Zembe, Lycias |
| collection | Thesis |
| description | Includes bibliographical references (leaves 114-147). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12731 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:40:33.582Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Virology |
| publisherStr | Division of Virology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12731 Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa Zembe, Lycias Burgers, Wendy Medical Virology Includes bibliographical references (leaves 114-147). The increasing diversity of HIV-1 in different geographic regions presents a challenge for the development of an HIV/AIDS vaccine. Even if proven effective, the ability of a vaccine to have cross-subtype and intra-subtype protection remains an important question. The aim of the study was to investigate cross- and intra-clade T cell immune responses in HIV-1 subtype C-infected individuals. The objectives were to genetically characterise full length gag gene sequences from individuals chronically infected with HIV-1 and then assess the degree of cross-reactive immune responses in an ELlS pot assay using peptide reagents based on vaccine candidates. 2015-05-06T07:11:00Z 2015-05-06T07:11:00Z 2007 Master Thesis Masters MSc http://hdl.handle.net/11427/12731 eng application/pdf Division of Virology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medical Virology Zembe, Lycias Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa |
| thesis_degree_str | Master's |
| title | Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa |
| title_full | Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa |
| title_fullStr | Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa |
| title_full_unstemmed | Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa |
| title_short | Investigating cross-clade immune responses in HIV-1 subtype C-infected individuals from South Africa |
| title_sort | investigating cross clade immune responses in hiv 1 subtype c infected individuals from south africa |
| topic | Medical Virology |
| url | http://hdl.handle.net/11427/12731 |
| work_keys_str_mv | AT zembelycias investigatingcrosscladeimmuneresponsesinhiv1subtypecinfectedindividualsfromsouthafrica |