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The separation of diastereoisomers by gas-liquid chromatography
The preparation and the gas chromatographic behaviour of several series of diastereoisomeric compounds is described. The series are the following: (1) Alkyl lactates, {2) Afkyl á-alkanoyloxypropionates, (3) Dialkyl esters of 2,3-butanediol, (4) Di-(haloacetic) esters of 2 1 3-butanediol and (5) á,â-...
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| Format: | Thesis |
| Language: | English |
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Department of Chemistry
2015
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| _version_ | 1867613219774791680 |
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| access_status_str | Open Access |
| author | Nurok, David |
| author2 | Stephen, A M |
| author_browse | Nurok, David Stephen, A M |
| author_facet | Stephen, A M Nurok, David |
| author_sort | Nurok, David |
| collection | Thesis |
| description | The preparation and the gas chromatographic behaviour of several series of diastereoisomeric compounds is described. The series are the following: (1) Alkyl lactates, {2) Afkyl á-alkanoyloxypropionates, (3) Dialkyl esters of 2,3-butanediol, (4) Di-(haloacetic) esters of 2 1 3-butanediol and (5) á,â-Diols. Chromatography was performed at various temperatures and a variety of stationary phases was used. Capillary columns were used for chromatography of series 1 and 2 whereas packed columns were used for series 3 to 5. It was found that for all of the above series nearly all of th compounds could be separated into diastereoisomers. The separability was found to be a function of the chemical structure of the compounds, of the polarity of the stationary phases and of the temperature at which chromatography was performed. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/13520 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:39.476Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/13520 The separation of diastereoisomers by gas-liquid chromatography Nurok, David Stephen, A M Chemistry The preparation and the gas chromatographic behaviour of several series of diastereoisomeric compounds is described. The series are the following: (1) Alkyl lactates, {2) Afkyl á-alkanoyloxypropionates, (3) Dialkyl esters of 2,3-butanediol, (4) Di-(haloacetic) esters of 2 1 3-butanediol and (5) á,â-Diols. Chromatography was performed at various temperatures and a variety of stationary phases was used. Capillary columns were used for chromatography of series 1 and 2 whereas packed columns were used for series 3 to 5. It was found that for all of the above series nearly all of th compounds could be separated into diastereoisomers. The separability was found to be a function of the chemical structure of the compounds, of the polarity of the stationary phases and of the temperature at which chromatography was performed. 2015-07-14T09:02:43Z 2015-07-14T09:02:43Z 1966 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/13520 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry Nurok, David The separation of diastereoisomers by gas-liquid chromatography |
| thesis_degree_str | Doctoral |
| title | The separation of diastereoisomers by gas-liquid chromatography |
| title_full | The separation of diastereoisomers by gas-liquid chromatography |
| title_fullStr | The separation of diastereoisomers by gas-liquid chromatography |
| title_full_unstemmed | The separation of diastereoisomers by gas-liquid chromatography |
| title_short | The separation of diastereoisomers by gas-liquid chromatography |
| title_sort | separation of diastereoisomers by gas liquid chromatography |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/13520 |
| work_keys_str_mv | AT nurokdavid theseparationofdiastereoisomersbygasliquidchromatography AT nurokdavid separationofdiastereoisomersbygasliquidchromatography |