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Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study

Background: Recent international guidelines call for universal use of triple-drug antiretroviral therapy (ART) in HIV-infected women during pregnancy and postpartum. There are however concerns regarding potentially high levels of non-adherence and/or loss to follow-up (LTF) that may attenuate the be...

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Main Author: Phillips, Tammy
Other Authors: Myer, Landon
Format: Thesis
Language:English
Published: Department of Public Health and Family Medicine 2015
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access_status_str Open Access
author Phillips, Tammy
author2 Myer, Landon
author_browse Myer, Landon
Phillips, Tammy
author_facet Myer, Landon
Phillips, Tammy
author_sort Phillips, Tammy
collection Thesis
description Background: Recent international guidelines call for universal use of triple-drug antiretroviral therapy (ART) in HIV-infected women during pregnancy and postpartum. There are however concerns regarding potentially high levels of non-adherence and/or loss to follow-up (LTF) that may attenuate the benefits of ART for HIV transmission and maternal health. We investigated missed visits and LTF among women initiating ART during pregnancy in Cape Town, South Africa. Methodology: A retrospective cohort study was conducted of women starting ART between January 2011 and September 2012, at a large primary care antenatal clinic. Eligible women were identified in prevention of mother-to-child transmission (PMTCT) services based on CD4 ≤350 cells/μl, and women initiated a regimen of tenofovir, lamivudine and efavirenz. Women eligible for ART were either referred to general adult ART services nearby (January-December 2011) or received ART integrated into ANC services (January-September 2012). Outcomes were measured up to six months postpartum: (i) LTF (no attendance within 56 days of a scheduled visit) and (ii) missed visit (returning to care 14-56 days late for a scheduled visit).
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license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
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spelling oai:open.uct.ac.za:11427/13977 Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study Phillips, Tammy Myer, Landon McIntyre, James Epidemiology Background: Recent international guidelines call for universal use of triple-drug antiretroviral therapy (ART) in HIV-infected women during pregnancy and postpartum. There are however concerns regarding potentially high levels of non-adherence and/or loss to follow-up (LTF) that may attenuate the benefits of ART for HIV transmission and maternal health. We investigated missed visits and LTF among women initiating ART during pregnancy in Cape Town, South Africa. Methodology: A retrospective cohort study was conducted of women starting ART between January 2011 and September 2012, at a large primary care antenatal clinic. Eligible women were identified in prevention of mother-to-child transmission (PMTCT) services based on CD4 ≤350 cells/μl, and women initiated a regimen of tenofovir, lamivudine and efavirenz. Women eligible for ART were either referred to general adult ART services nearby (January-December 2011) or received ART integrated into ANC services (January-September 2012). Outcomes were measured up to six months postpartum: (i) LTF (no attendance within 56 days of a scheduled visit) and (ii) missed visit (returning to care 14-56 days late for a scheduled visit). 2015-09-15T10:26:12Z 2015-09-15T10:26:12Z 2014 Master Thesis Masters MPH http://hdl.handle.net/11427/13977 eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Epidemiology
Phillips, Tammy
Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study
thesis_degree_str Master's
title Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study
title_full Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study
title_fullStr Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study
title_full_unstemmed Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study
title_short Retention in care among HIV-infected women initiating ART during pregnancy: a cohort study
title_sort retention in care among hiv infected women initiating art during pregnancy a cohort study
topic Epidemiology
url http://hdl.handle.net/11427/13977
work_keys_str_mv AT phillipstammy retentionincareamonghivinfectedwomeninitiatingartduringpregnancyacohortstudy