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Synthesis and selective reactivity of 14β-formyl 19-norsteroids

A synthetic route to 3-methoxy-16-methyl-14,17α-ethanoestra-1,3,5(10)-triene-15,16,l 7β3-triol 17β3-acetate was devised, based upon cycloaddition of a dienophilic 'propyne equivalent' to 3-methoxyestra-1,3,5(10),14,16-pentaen-17-yl acetate. The dienophile chosen for this purpose, methyl propiolate,...

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Bibliographic Details
Main Author: Hoadley, Clarissa
Other Authors: Bull, James R
Format: Thesis
Language:English
Published: Department of Chemistry 2016
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