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Pharmacokinetics, pharmacogenetics and optimisation of treatment with non-nucleoside reverse transcriptase inhibitors in HIV-infected African children

Efavirenz and nevirapine are the most widely used agents for treatment of HIV in children. Sources of variability in their pharmacokinetics and its association with virological outcome and adverse events in African children are poorly characterised, thereby limiting treatment optimisation. To fill t...

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Bibliographic Details
Main Author: Bienczak, Andrzej Marek
Other Authors: Denti, Paolo
Format: Thesis
Language:English
Published: Division of Clinical Pharmacology 2017
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