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Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas

The fact therefore remains that, at the present time, Crohn's disease is still an enigma. The aetiology and pathogenesis are obscure, the clinical findings and progression of the disease are unpredictable and the histological findings are often nonspecific. With this in mind, this dissertation attem...

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Main Author: Forder, Michael David
Other Authors: Price, S K
Format: Thesis
Language:English
Published: Division of Anatomical Pathology 2017
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access_status_str Open Access
author Forder, Michael David
author2 Price, S K
author_browse Forder, Michael David
Price, S K
author_facet Price, S K
Forder, Michael David
author_sort Forder, Michael David
collection Thesis
description The fact therefore remains that, at the present time, Crohn's disease is still an enigma. The aetiology and pathogenesis are obscure, the clinical findings and progression of the disease are unpredictable and the histological findings are often nonspecific. With this in mind, this dissertation attempts to define and document the incidence of certain histological features at presentation in a population of Crohn's disease patients from Groote Schuur Hospital. The main aim is to determine the incidence of granulomas in the study group as a whole, as well as to establish the distribution of granulomas within the bowel. A correlation between the presence of granulomas and the clinical activity of the disease (as assessed by the Crohn's Disease Activity Index) is also sought.
format Thesis
id oai:open.uct.ac.za:11427/25570
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:52:23.074Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2017
publishDateRange 2017
publishDateSort 2017
publisher Division of Anatomical Pathology
publisherStr Division of Anatomical Pathology
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/25570 Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas Forder, Michael David Price, S K Crohn's Disease - diagnosis~Granuloma The fact therefore remains that, at the present time, Crohn's disease is still an enigma. The aetiology and pathogenesis are obscure, the clinical findings and progression of the disease are unpredictable and the histological findings are often nonspecific. With this in mind, this dissertation attempts to define and document the incidence of certain histological features at presentation in a population of Crohn's disease patients from Groote Schuur Hospital. The main aim is to determine the incidence of granulomas in the study group as a whole, as well as to establish the distribution of granulomas within the bowel. A correlation between the presence of granulomas and the clinical activity of the disease (as assessed by the Crohn's Disease Activity Index) is also sought. 2017-10-11T10:52:02Z 2017-10-11T10:52:02Z 1992 2017-07-12T09:09:52Z Master Thesis Masters MMed http://hdl.handle.net/11427/25570 eng application/pdf Division of Anatomical Pathology Faculty of Health Sciences University of Cape Town
spellingShingle Crohn's Disease - diagnosis~Granuloma
Forder, Michael David
Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
thesis_degree_str Master's
title Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
title_full Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
title_fullStr Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
title_full_unstemmed Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
title_short Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
title_sort crohn s disease diagnostic and prognostic indicators with special reference to granulomas
topic Crohn's Disease - diagnosis~Granuloma
url http://hdl.handle.net/11427/25570
work_keys_str_mv AT fordermichaeldavid crohnsdiseasediagnosticandprognosticindicatorswithspecialreferencetogranulomas