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Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension

The diagnosis of primary pulmonary hypertension (PPH) and prediction of its course, whether treated or untreated, presents several problems. These are of particular relevance when selection of patients for, and timing of heart-lung transplantation is being considered. I performed a retrospective stu...

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Main Author: Chapman, P J
Other Authors: Benatar, Solomon R
Format: Thesis
Language:English
Published: Division of Pulmonology 2017
Subjects:
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access_status_str Open Access
author Chapman, P J
author2 Benatar, Solomon R
author_browse Benatar, Solomon R
Chapman, P J
author_facet Benatar, Solomon R
Chapman, P J
author_sort Chapman, P J
collection Thesis
description The diagnosis of primary pulmonary hypertension (PPH) and prediction of its course, whether treated or untreated, presents several problems. These are of particular relevance when selection of patients for, and timing of heart-lung transplantation is being considered. I performed a retrospective study on patients with PPH and chronic large vessel thromboembolic pulmonary hypertension (TPH) seen at Groote Schuur Hospital between 1957 and 1985 in an attempt to: 1. Establish the diagnostic and prognostic value of clinical features, lung function tests, cardiac catheterisation, isotope lung scans and, in the PPH group, response to therapy; 2. Review our experience of the effects of treatment with vasodilators and oral anticoagulants, and the results of heart and lung transplantation in the PPH group; 3. Attempt to identify features which could be used to predict prognosis in PPH; and thereby 4. Define criteria for selecting PPH patients whose prognosis could be improved by heart-lung transplantation.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:47:57.480Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2017
publishDateRange 2017
publishDateSort 2017
publisher Division of Pulmonology
publisherStr Division of Pulmonology
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/25726 Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension Chapman, P J Benatar, Solomon R Bateman, Eric D Pulmonary hypertension Pulmonology The diagnosis of primary pulmonary hypertension (PPH) and prediction of its course, whether treated or untreated, presents several problems. These are of particular relevance when selection of patients for, and timing of heart-lung transplantation is being considered. I performed a retrospective study on patients with PPH and chronic large vessel thromboembolic pulmonary hypertension (TPH) seen at Groote Schuur Hospital between 1957 and 1985 in an attempt to: 1. Establish the diagnostic and prognostic value of clinical features, lung function tests, cardiac catheterisation, isotope lung scans and, in the PPH group, response to therapy; 2. Review our experience of the effects of treatment with vasodilators and oral anticoagulants, and the results of heart and lung transplantation in the PPH group; 3. Attempt to identify features which could be used to predict prognosis in PPH; and thereby 4. Define criteria for selecting PPH patients whose prognosis could be improved by heart-lung transplantation. 2017-10-23T06:37:59Z 2017-10-23T06:37:59Z 1987 2017-07-20T13:03:33Z Master Thesis Masters MMed http://hdl.handle.net/11427/25726 eng application/pdf Division of Pulmonology Faculty of Health Sciences University of Cape Town
spellingShingle Pulmonary hypertension
Pulmonology
Chapman, P J
Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
thesis_degree_str Master's
title Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
title_full Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
title_fullStr Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
title_full_unstemmed Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
title_short Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
title_sort diagnostic prognostic and therapeutic considerations in primary pulmonary hypertension
topic Pulmonary hypertension
Pulmonology
url http://hdl.handle.net/11427/25726
work_keys_str_mv AT chapmanpj diagnosticprognosticandtherapeuticconsiderationsinprimarypulmonaryhypertension