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The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis
This study was designed to: 1. Examine the diagnostic value of ADA levels in ascitic fluid, 2. Establish the sensitivity and specificity of this test in the diagnosis of tuberculous peritonitis, in a large number of patients, 3. Establish levels of adenosine deaminase activity which give the best di...
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| Format: | Thesis |
| Language: | English |
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Department of Medicine
2017
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| _version_ | 1867613305782140928 |
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| access_status_str | Open Access |
| author | Voigt, Michael D |
| author_browse | Voigt, Michael D |
| author_facet | Voigt, Michael D |
| author_sort | Voigt, Michael D |
| collection | Thesis |
| description | This study was designed to: 1. Examine the diagnostic value of ADA levels in ascitic fluid, 2. Establish the sensitivity and specificity of this test in the diagnosis of tuberculous peritonitis, in a large number of patients, 3. Establish levels of adenosine deaminase activity which give the best discriminatory information in patients with ascites. 4. Determine what conditions may give rise to false positive or false negative results. 5. Finally, the study was designed to assess the relative diagnostic accuracy of previously used biochemical and haematological data, such as ascites total protein and white cell count. The diagnostic value of these tests alone, and combined with ADA activity in a descriminant analysis, was compared with the diagnostic accuracy of adenosine deaminase activity alone. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/25882 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:00.978Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/25882 The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis Voigt, Michael D Peritoneum - Tuberculosis Ascites Adenosine This study was designed to: 1. Examine the diagnostic value of ADA levels in ascitic fluid, 2. Establish the sensitivity and specificity of this test in the diagnosis of tuberculous peritonitis, in a large number of patients, 3. Establish levels of adenosine deaminase activity which give the best discriminatory information in patients with ascites. 4. Determine what conditions may give rise to false positive or false negative results. 5. Finally, the study was designed to assess the relative diagnostic accuracy of previously used biochemical and haematological data, such as ascites total protein and white cell count. The diagnostic value of these tests alone, and combined with ADA activity in a descriminant analysis, was compared with the diagnostic accuracy of adenosine deaminase activity alone. 2017-10-30T06:53:18Z 2017-10-30T06:53:18Z 1988 2017-03-29T14:28:57Z Master Thesis Masters MMed http://hdl.handle.net/11427/25882 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Peritoneum - Tuberculosis Ascites Adenosine Voigt, Michael D The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis |
| thesis_degree_str | Master's |
| title | The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis |
| title_full | The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis |
| title_fullStr | The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis |
| title_full_unstemmed | The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis |
| title_short | The diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis |
| title_sort | diagnostic value of adenosine deaminase activity in the ascitic fluid of patients with tuberculous peritonitis |
| topic | Peritoneum - Tuberculosis Ascites Adenosine |
| url | http://hdl.handle.net/11427/25882 |
| work_keys_str_mv | AT voigtmichaeld thediagnosticvalueofadenosinedeaminaseactivityintheasciticfluidofpatientswithtuberculousperitonitis AT voigtmichaeld diagnosticvalueofadenosinedeaminaseactivityintheasciticfluidofpatientswithtuberculousperitonitis |