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Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course

Patients were selected for the study on the basis of 1: A diagnosis of systemic Lupus Erythematosus according to the 1982 revised American Rheumatology Association criteria47 and 2: An adequate biopsy defined as containing at least six glomeruli. Patients were biopsied at Groote Schuur Hospital duri...

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Main Author: Van Diggelen, Nicholas Tromp
Other Authors: Tiltman, A J
Format: Thesis
Language:English
Published: Division of Anatomical Pathology 2017
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access_status_str Open Access
author Van Diggelen, Nicholas Tromp
author2 Tiltman, A J
author_browse Tiltman, A J
Van Diggelen, Nicholas Tromp
author_facet Tiltman, A J
Van Diggelen, Nicholas Tromp
author_sort Van Diggelen, Nicholas Tromp
collection Thesis
description Patients were selected for the study on the basis of 1: A diagnosis of systemic Lupus Erythematosus according to the 1982 revised American Rheumatology Association criteria47 and 2: An adequate biopsy defined as containing at least six glomeruli. Patients were biopsied at Groote Schuur Hospital during the period 1978 to 1988 and the indications for renal biopsy were clinical based on laboratory results of renal function. Patients were followed between 1 and 120 months with a mean observation period of 34 months. The clinical records were scrutinised and the following pa·rameters were noted at the time of biopsy: age, sex, race, time from diagnosis to biopsy, serum urea, creatinine, creatinine clearence and urinary 24 hour protein. Using the latest serum urea, creatinine, creatinine clearence and / or 24 hour urinary protein where available, outcome was graded as: 1: An improvement in renal function 2: A stable renal function 3: Deterioration in renal function 4: Patient on dialysis 5: Death due to disease.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:32:18.917Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2017
publishDateRange 2017
publishDateSort 2017
publisher Division of Anatomical Pathology
publisherStr Division of Anatomical Pathology
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/25897 Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course Van Diggelen, Nicholas Tromp Tiltman, A J Systemic lupus erythematosus - Complications and sequelae Kidneys - Diseases - Complications and sequelae Kidney diseases - Complications Lupus Erythematosus, Systemic - complications Lupus Nephr Patients were selected for the study on the basis of 1: A diagnosis of systemic Lupus Erythematosus according to the 1982 revised American Rheumatology Association criteria47 and 2: An adequate biopsy defined as containing at least six glomeruli. Patients were biopsied at Groote Schuur Hospital during the period 1978 to 1988 and the indications for renal biopsy were clinical based on laboratory results of renal function. Patients were followed between 1 and 120 months with a mean observation period of 34 months. The clinical records were scrutinised and the following pa·rameters were noted at the time of biopsy: age, sex, race, time from diagnosis to biopsy, serum urea, creatinine, creatinine clearence and urinary 24 hour protein. Using the latest serum urea, creatinine, creatinine clearence and / or 24 hour urinary protein where available, outcome was graded as: 1: An improvement in renal function 2: A stable renal function 3: Deterioration in renal function 4: Patient on dialysis 5: Death due to disease. 2017-10-30T10:38:33Z 2017-10-30T10:38:33Z 1989 2017-03-30T10:13:35Z Master Thesis Masters MMed http://hdl.handle.net/11427/25897 eng application/pdf Division of Anatomical Pathology Faculty of Health Sciences University of Cape Town
spellingShingle Systemic lupus erythematosus - Complications and sequelae
Kidneys - Diseases - Complications and sequelae
Kidney diseases - Complications
Lupus Erythematosus, Systemic - complications
Lupus Nephr
Van Diggelen, Nicholas Tromp
Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course
thesis_degree_str Master's
title Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course
title_full Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course
title_fullStr Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course
title_full_unstemmed Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course
title_short Renal disease in systemic lupus erythematosus: correlation of morphology with clinical course
title_sort renal disease in systemic lupus erythematosus correlation of morphology with clinical course
topic Systemic lupus erythematosus - Complications and sequelae
Kidneys - Diseases - Complications and sequelae
Kidney diseases - Complications
Lupus Erythematosus, Systemic - complications
Lupus Nephr
url http://hdl.handle.net/11427/25897
work_keys_str_mv AT vandiggelennicholastromp renaldiseaseinsystemiclupuserythematosuscorrelationofmorphologywithclinicalcourse