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Postradiation sarcomas
This report from Groote Schuur therefore sets out to review cases of postradiation sarcomas, including malignant mixed mullerian tumors (MMMT), presenting to the Radiation Oncology Departments of Groote Schuur Hospital and the affiliated hospitals (Frere Hospital, East London and Provincial Hospital...
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| Format: | Thesis |
| Language: | English |
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Division of Radiation Oncology
2017
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| _version_ | 1867613310317232128 |
|---|---|
| access_status_str | Open Access |
| author | Murray, Elizabeth Margaret |
| author2 | Werner, I D |
| author_browse | Murray, Elizabeth Margaret Werner, I D |
| author_facet | Werner, I D Murray, Elizabeth Margaret |
| author_sort | Murray, Elizabeth Margaret |
| collection | Thesis |
| description | This report from Groote Schuur therefore sets out to review cases of postradiation sarcomas, including malignant mixed mullerian tumors (MMMT), presenting to the Radiation Oncology Departments of Groote Schuur Hospital and the affiliated hospitals (Frere Hospital, East London and Provincial Hospital, Port Elizabeth) or known to have occurred in patients initially treated in these hospitals. It aims [1] to establish the features of the initial malignancy as well as the latent period for the development of postradiation sarcoma, the type of postradiation tumor and the outcome of the disease; [2] to establish as accurately as possible dose levels at which the postradiation tumors have developed; and [3] to briefly describe possible risk factors such as a genetic predisposition to the development of malignancy, repeated courses of radiotherapy, surgery as part of the treatment of the initial tumor, and chemotherapy. Questions regarding the genesis of postradiation sarcomas cannot be answered by a review of 20 cases, even when combined with an analysis of literature. This review aims to add relevant information to the body of data from which the final answers may come. In view of the late diagnosis often made in cases of postradiation sarcoma (25, 94) the review also aims to heighten awareness of the condition so that it may be more often reported at a curable stage. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/26150 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:06.076Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Division of Radiation Oncology |
| publisherStr | Division of Radiation Oncology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/26150 Postradiation sarcomas Murray, Elizabeth Margaret Werner, I D Neoplasms - radiotherapy Radiation effects Radiotherapy - Adverse effects Sarcoma - etiology Sarcoma - Pathology This report from Groote Schuur therefore sets out to review cases of postradiation sarcomas, including malignant mixed mullerian tumors (MMMT), presenting to the Radiation Oncology Departments of Groote Schuur Hospital and the affiliated hospitals (Frere Hospital, East London and Provincial Hospital, Port Elizabeth) or known to have occurred in patients initially treated in these hospitals. It aims [1] to establish the features of the initial malignancy as well as the latent period for the development of postradiation sarcoma, the type of postradiation tumor and the outcome of the disease; [2] to establish as accurately as possible dose levels at which the postradiation tumors have developed; and [3] to briefly describe possible risk factors such as a genetic predisposition to the development of malignancy, repeated courses of radiotherapy, surgery as part of the treatment of the initial tumor, and chemotherapy. Questions regarding the genesis of postradiation sarcomas cannot be answered by a review of 20 cases, even when combined with an analysis of literature. This review aims to add relevant information to the body of data from which the final answers may come. In view of the late diagnosis often made in cases of postradiation sarcoma (25, 94) the review also aims to heighten awareness of the condition so that it may be more often reported at a curable stage. 2017-11-10T09:57:27Z 2017-11-10T09:57:27Z 1995 2017-05-09T13:59:43Z Master Thesis Masters MMed http://hdl.handle.net/11427/26150 eng application/pdf Division of Radiation Oncology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Neoplasms - radiotherapy Radiation effects Radiotherapy - Adverse effects Sarcoma - etiology Sarcoma - Pathology Murray, Elizabeth Margaret Postradiation sarcomas |
| thesis_degree_str | Master's |
| title | Postradiation sarcomas |
| title_full | Postradiation sarcomas |
| title_fullStr | Postradiation sarcomas |
| title_full_unstemmed | Postradiation sarcomas |
| title_short | Postradiation sarcomas |
| title_sort | postradiation sarcomas |
| topic | Neoplasms - radiotherapy Radiation effects Radiotherapy - Adverse effects Sarcoma - etiology Sarcoma - Pathology |
| url | http://hdl.handle.net/11427/26150 |
| work_keys_str_mv | AT murrayelizabethmargaret postradiationsarcomas |