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Role of envelope compactness and glycosylation in HIV-1 resistance to neutralising antibody responses

Understanding the mechanisms used by HIV-1 to evade antibody neutralisation may contribute to the design of a high-coverage vaccine. This thesis explores the mechanism used by a Tier 3 virus leading to its high antibody neutralisation resistance phenotype. This thesis also describes how the glycans...

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Bibliographic Details
Main Author: Moyo, Thandeka
Other Authors: Dorfman, Jeffrey R
Format: Thesis
Language:English
Published: Division of Immunology 2018
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