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The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results

This study was conducted with the support of the Combined Breast Clinic at our institution which consists of the Departments of Surgery, Radiology and Radiation Oncology. The work was done in three parts. The literature showed somewhat lengthy imaging procedure for scintimammography which were not w...

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Main Author: Nizami, Mohammad Athar Farooq
Other Authors: Mann, Michael D
Format: Thesis
Language:English
Published: Division of Nuclear Medicine 2018
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access_status_str Open Access
author Nizami, Mohammad Athar Farooq
author2 Mann, Michael D
author_browse Mann, Michael D
Nizami, Mohammad Athar Farooq
author_facet Mann, Michael D
Nizami, Mohammad Athar Farooq
author_sort Nizami, Mohammad Athar Farooq
collection Thesis
description This study was conducted with the support of the Combined Breast Clinic at our institution which consists of the Departments of Surgery, Radiology and Radiation Oncology. The work was done in three parts. The literature showed somewhat lengthy imaging procedure for scintimammography which were not whole suitable to the setting of the Combined Breast Clinic. Initially a Pilot Study was conducted to determine the practicality of the imaging procedure. The results of this study were promising but the imaging procedure was time consuming. Certain modifications were subsequently done in the imaging method of the Formal Study to accommodate more number of patients into the study without jeopardizing the quality of the images. This study, however, had a shortcoming in that the way this study was structured one could not demonstrate lesion by lesion analysis of each breast lesion detected on clinical examination, mammography and scintimammography with their respective biopsy results. Our Formal Study and the literature suggested that scintimammography is of value in patients with indeterminate mammograms due to its high negative predictive value. Therefore, a separate Additional Study, with the same scintigraphic method, was conducted on patients with clinical breast lumps with indeterminate mammographic lesions. Special emphasis was placed on lesion by lesion comparison of each breast lesion detected by clinical examination or scintimammography or both with the biopsy results of that particular lesion.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:33:15.376Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2018
publishDateRange 2018
publishDateSort 2018
publisher Division of Nuclear Medicine
publisherStr Division of Nuclear Medicine
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/26922 The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results Nizami, Mohammad Athar Farooq Mann, Michael D Dent, David Marshall Adams, Bruce K Nuclear Medicine This study was conducted with the support of the Combined Breast Clinic at our institution which consists of the Departments of Surgery, Radiology and Radiation Oncology. The work was done in three parts. The literature showed somewhat lengthy imaging procedure for scintimammography which were not whole suitable to the setting of the Combined Breast Clinic. Initially a Pilot Study was conducted to determine the practicality of the imaging procedure. The results of this study were promising but the imaging procedure was time consuming. Certain modifications were subsequently done in the imaging method of the Formal Study to accommodate more number of patients into the study without jeopardizing the quality of the images. This study, however, had a shortcoming in that the way this study was structured one could not demonstrate lesion by lesion analysis of each breast lesion detected on clinical examination, mammography and scintimammography with their respective biopsy results. Our Formal Study and the literature suggested that scintimammography is of value in patients with indeterminate mammograms due to its high negative predictive value. Therefore, a separate Additional Study, with the same scintigraphic method, was conducted on patients with clinical breast lumps with indeterminate mammographic lesions. Special emphasis was placed on lesion by lesion comparison of each breast lesion detected by clinical examination or scintimammography or both with the biopsy results of that particular lesion. 2018-01-24T11:47:36Z 2018-01-24T11:47:36Z 1999 Master Thesis Masters MMed http://hdl.handle.net/11427/26922 eng application/pdf Division of Nuclear Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Nuclear Medicine
Nizami, Mohammad Athar Farooq
The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results
thesis_degree_str Master's
title The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results
title_full The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results
title_fullStr The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results
title_full_unstemmed The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results
title_short The role of Technetium-99m Sestamibi scintimammography to evaluate palpable breast lesions : a comparison with mammography and histological results
title_sort role of technetium 99m sestamibi scintimammography to evaluate palpable breast lesions a comparison with mammography and histological results
topic Nuclear Medicine
url http://hdl.handle.net/11427/26922
work_keys_str_mv AT nizamimohammadatharfarooq theroleoftechnetium99msestamibiscintimammographytoevaluatepalpablebreastlesionsacomparisonwithmammographyandhistologicalresults
AT nizamimohammadatharfarooq roleoftechnetium99msestamibiscintimammographytoevaluatepalpablebreastlesionsacomparisonwithmammographyandhistologicalresults