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The Development and Validation of a Direct LC-MS/MS Assay for the Determination of Tenofovir-diphosphate in Dried Blood Spots for the Analysis of Clinical Samples

Tenofovir (TFV) and emtricitabine (FTC) are nucleoside reverse transcriptase inhibitors, often used in preexposure prophylaxis (PrEP) trials: where antiretroviral drugs are administered to high-risk, HIV-negative individuals to prevent HIV infection. Both drugs are safe when taken either daily or in...

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Bibliographic Details
Main Author: Oberholster, Lucas
Other Authors: Wiesner, Lubbe
Format: Thesis
Language:English
Published: Division of Clinical Pharmacology 2020
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