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Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa

Includes abstract.

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Bibliographic Details
Main Author: Matejcic, Marco
Other Authors: Parker, M Iqbal
Format: Thesis
Language:English
Published: Division of Medical Biochemistry 2014
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access_status_str Open Access
author Matejcic, Marco
author2 Parker, M Iqbal
author_browse Matejcic, Marco
Parker, M Iqbal
author_facet Parker, M Iqbal
Matejcic, Marco
author_sort Matejcic, Marco
collection Thesis
description Includes abstract.
format Thesis
id oai:open.uct.ac.za:11427/3139
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:31:41.113Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Division of Medical Biochemistry
publisherStr Division of Medical Biochemistry
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/3139 Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa Matejcic, Marco Parker, M Iqbal Mathew, Chris Medical Biochemistry Includes abstract. Includes bibliographical references. Oesophageal squamous cell carcinoma (OSCC) is a complex disease, determined by the interaction of genetic factors with environmental risk factors. In South Africa, OSCC is a major malignancy occurring with high incidence in the Black and Mixed Ancestry populations. Previous studies by our research group have reported that genetic polymorphism of xenobiotic metabolizing enzymes influence greatly the detoxification of tobacco-related carcinogens in vivo, and may therefore have an important role in determining susceptibility to oesophageal cancer. 2014-07-28T14:55:42Z 2014-07-28T14:55:42Z 2013 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3139 eng application/pdf Division of Medical Biochemistry Faculty of Health Sciences University of Cape Town
spellingShingle Medical Biochemistry
Matejcic, Marco
Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa
thesis_degree_str Doctoral
title Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa
title_full Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa
title_fullStr Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa
title_full_unstemmed Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa
title_short Identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in South Africa
title_sort identification of genetic polymorphisms associated with oesophageal squamous cell carcinoma risk in south africa
topic Medical Biochemistry
url http://hdl.handle.net/11427/3139
work_keys_str_mv AT matejcicmarco identificationofgeneticpolymorphismsassociatedwithoesophagealsquamouscellcarcinomariskinsouthafrica