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Clot retraction

The haemorrhagic disorders form only a small, although often most alarming part of the diseases inflicted upon mankind, and in spite of the enthusiasm of the disproportionally great number of workers investigating the problem of the coagulation of the blood, this problem until quite recently could...

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Main Author: Budtz-Olsen, Otto Egede
Format: Thesis
Language:English
Published: Department of Pathology 2020
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access_status_str Open Access
author Budtz-Olsen, Otto Egede
author_browse Budtz-Olsen, Otto Egede
author_facet Budtz-Olsen, Otto Egede
author_sort Budtz-Olsen, Otto Egede
collection Thesis
description The haemorrhagic disorders form only a small, although often most alarming part of the diseases inflicted upon mankind, and in spite of the enthusiasm of the disproportionally great number of workers investigating the problem of the coagulation of the blood, this problem until quite recently could only be looked upon as being mainly of academic physiological interest. With the advent and daily increasing use of the highly dangerous anti-coagulant therapy for thrombosis and embolism, demanding at least a general understanding of the mechanism of blood clotting, every aspect of this mechanism has become of practical clinical importance, and no serious effort to clarify the question can be considered wasted. It is peculiar that the last phase of coagulation, the contraction of the clot, which is by no means the least spectacular, has received rather scanty attention compared to the enormous amount of work that has been expended on the earlier stages. No agreement exists with regard to the mechanism or purpose of clot retraction; the factors controlling it are to a large-extent unknown, and even the fundamental question of the part played by the platelets is undecided.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:36:56.144Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher Department of Pathology
publisherStr Department of Pathology
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/31917 Clot retraction Budtz-Olsen, Otto Egede Clot The haemorrhagic disorders form only a small, although often most alarming part of the diseases inflicted upon mankind, and in spite of the enthusiasm of the disproportionally great number of workers investigating the problem of the coagulation of the blood, this problem until quite recently could only be looked upon as being mainly of academic physiological interest. With the advent and daily increasing use of the highly dangerous anti-coagulant therapy for thrombosis and embolism, demanding at least a general understanding of the mechanism of blood clotting, every aspect of this mechanism has become of practical clinical importance, and no serious effort to clarify the question can be considered wasted. It is peculiar that the last phase of coagulation, the contraction of the clot, which is by no means the least spectacular, has received rather scanty attention compared to the enormous amount of work that has been expended on the earlier stages. No agreement exists with regard to the mechanism or purpose of clot retraction; the factors controlling it are to a large-extent unknown, and even the fundamental question of the part played by the platelets is undecided. 2020-05-18T16:24:43Z 2020-05-18T16:24:43Z 1951 2020-04-16T08:46:17Z Doctoral Thesis Doctoral https://hdl.handle.net/11427/31917 eng application/pdf Department of Pathology Faculty of Health Sciences
spellingShingle Clot
Budtz-Olsen, Otto Egede
Clot retraction
thesis_degree_str Doctoral
title Clot retraction
title_full Clot retraction
title_fullStr Clot retraction
title_full_unstemmed Clot retraction
title_short Clot retraction
title_sort clot retraction
topic Clot
url https://hdl.handle.net/11427/31917
work_keys_str_mv AT budtzolsenottoegede clotretraction