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Extracellular matrix gene sequence variant analyses and Achilles tendinopathy
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Human Biology
2014
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| _version_ | 1867613283361488896 |
|---|---|
| access_status_str | Open Access |
| author | Saunders, Colleen Jayne |
| author2 | September, Alison |
| author_browse | Saunders, Colleen Jayne September, Alison |
| author_facet | September, Alison Saunders, Colleen Jayne |
| author_sort | Saunders, Colleen Jayne |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3199 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:40.116Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3199 Extracellular matrix gene sequence variant analyses and Achilles tendinopathy Saunders, Colleen Jayne September, Alison Schwellnus, Martin Collins, Malcolm Human Biology Includes abstract. Includes bibliographical references) The primary aim of this thesis was to identify additional genetic elements predisposing individuals to risk of AT using a candidate gene, case-control genetic association approach, and to propose the biological mechanisms underlying this genetic risk. Candidate genes (COMP, THBS2, COL27A1, TNC, COL3A1, COL5A2 and COL5A3) were selected based on their chromosomal location and/or the biological function of their encoded proteins within the extracellular matrix (ECM) of the tendon. 2014-07-28T18:14:28Z 2014-07-28T18:14:28Z 2013 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3199 eng application/pdf Department of Human Biology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Human Biology Saunders, Colleen Jayne Extracellular matrix gene sequence variant analyses and Achilles tendinopathy |
| thesis_degree_str | Doctoral |
| title | Extracellular matrix gene sequence variant analyses and Achilles tendinopathy |
| title_full | Extracellular matrix gene sequence variant analyses and Achilles tendinopathy |
| title_fullStr | Extracellular matrix gene sequence variant analyses and Achilles tendinopathy |
| title_full_unstemmed | Extracellular matrix gene sequence variant analyses and Achilles tendinopathy |
| title_short | Extracellular matrix gene sequence variant analyses and Achilles tendinopathy |
| title_sort | extracellular matrix gene sequence variant analyses and achilles tendinopathy |
| topic | Human Biology |
| url | http://hdl.handle.net/11427/3199 |
| work_keys_str_mv | AT saunderscolleenjayne extracellularmatrixgenesequencevariantanalysesandachillestendinopathy |