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The plasma corticosteroids: their determination and normal variations

The current interest in the secretions of the adrenal cortex is shared by physiologist, physician and pharmacologists alike. such attention is not surprising in the case of a gland which is immediately essential to life, which can produce syndromes as varied as precocious puberty, virilisation; Addi...

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Main Author: Lewis, Barry
Format: Thesis
Language:English
Published: Division of Physiological Sciences 2020
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access_status_str Open Access
author Lewis, Barry
author_browse Lewis, Barry
author_facet Lewis, Barry
author_sort Lewis, Barry
collection Thesis
description The current interest in the secretions of the adrenal cortex is shared by physiologist, physician and pharmacologists alike. such attention is not surprising in the case of a gland which is immediately essential to life, which can produce syndromes as varied as precocious puberty, virilisation; Addison's disease; Cushing's syndrome, and the newly described hyperaldosteronism syndrome of Conn (1955), a gland which has been implicated in the parthenogenesis of diabetes (Hoet and Lukens, 195; Jackson, 1955), hypertension (Sepeika, 1948, 1955), pre-eclampsia, and atherosclerosis, and which profoundly effects so many of the metabolic processes of the body. The need for accurate measurement of adrenocortical function has therefore been accentuated in recent years. The purpose of this study was to find out as direct a method as possible for determining the rate of secretion of this gland and to define with this method the norms and normal variations.
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institution University of Cape Town (South Africa)
language eng
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license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher Division of Physiological Sciences
publisherStr Division of Physiological Sciences
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/32040 The plasma corticosteroids: their determination and normal variations Lewis, Barry Adrenal Cortex Hormones The current interest in the secretions of the adrenal cortex is shared by physiologist, physician and pharmacologists alike. such attention is not surprising in the case of a gland which is immediately essential to life, which can produce syndromes as varied as precocious puberty, virilisation; Addison's disease; Cushing's syndrome, and the newly described hyperaldosteronism syndrome of Conn (1955), a gland which has been implicated in the parthenogenesis of diabetes (Hoet and Lukens, 195; Jackson, 1955), hypertension (Sepeika, 1948, 1955), pre-eclampsia, and atherosclerosis, and which profoundly effects so many of the metabolic processes of the body. The need for accurate measurement of adrenocortical function has therefore been accentuated in recent years. The purpose of this study was to find out as direct a method as possible for determining the rate of secretion of this gland and to define with this method the norms and normal variations. 2020-06-08T09:17:22Z 2020-06-08T09:17:22Z 1956 2020-04-08T10:10:59Z Doctoral Thesis Doctoral https://hdl.handle.net/11427/32040 eng application/pdf Division of Physiological Sciences Faculty of Health Sciences
spellingShingle Adrenal Cortex Hormones
Lewis, Barry
The plasma corticosteroids: their determination and normal variations
thesis_degree_str Doctoral
title The plasma corticosteroids: their determination and normal variations
title_full The plasma corticosteroids: their determination and normal variations
title_fullStr The plasma corticosteroids: their determination and normal variations
title_full_unstemmed The plasma corticosteroids: their determination and normal variations
title_short The plasma corticosteroids: their determination and normal variations
title_sort plasma corticosteroids their determination and normal variations
topic Adrenal Cortex Hormones
url https://hdl.handle.net/11427/32040
work_keys_str_mv AT lewisbarry theplasmacorticosteroidstheirdeterminationandnormalvariations
AT lewisbarry plasmacorticosteroidstheirdeterminationandnormalvariations