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Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Human Biology
2014
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| _version_ | 1867613231510454272 |
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| access_status_str | Open Access |
| author | Mokone, Gaonyadiwe George |
| author2 | Collins, Malcolm |
| author_browse | Collins, Malcolm Mokone, Gaonyadiwe George |
| author_facet | Collins, Malcolm Mokone, Gaonyadiwe George |
| author_sort | Mokone, Gaonyadiwe George |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3270 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:51.499Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3270 Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors Mokone, Gaonyadiwe George Collins, Malcolm Schwellnus, Martin Human Biology Includes bibliographical references. This main purpose of this thesis was therefore to investigate whether any specific genes on the tip of the long arm of chromosome 9 were associated with Achilles tendon injuries, using a case-control study design. The specific objectives were: (i) to identify all genes located in the 9q32-q34.3 locus in close proximity to the ABO gene, that could be involved in tendon injuries (Chapter 2) and (ii) to investigate the possible association of the identified candidate genes (COL5A1 and TNC with both Achilles tendon rupture and chronic Achilles tendinopathy (Chapter 3 and 4) and (iii) finally to investigate the possible interaction of these two genes with tendon function, namely the muscle-tendon unit flexibility (chapter 5) and structure, namely the morphological changes of the Achilles tendon (Chapter 6). 2014-07-28T18:17:33Z 2014-07-28T18:17:33Z 2006 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3270 eng application/pdf Department of Human Biology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Human Biology Mokone, Gaonyadiwe George Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors |
| thesis_degree_str | Doctoral |
| title | Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors |
| title_full | Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors |
| title_fullStr | Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors |
| title_full_unstemmed | Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors |
| title_short | Risk factors for Achilles tendon injuries : an emphasis on the identification of specific genetic factors |
| title_sort | risk factors for achilles tendon injuries an emphasis on the identification of specific genetic factors |
| topic | Human Biology |
| url | http://hdl.handle.net/11427/3270 |
| work_keys_str_mv | AT mokonegaonyadiwegeorge riskfactorsforachillestendoninjuriesanemphasisontheidentificationofspecificgeneticfactors |