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The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells
Includes bibliographical references (leaves 92-109).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Division of Clinical Pharmacology
2014
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| _version_ | 1867613173971943424 |
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| access_status_str | Open Access |
| author | Roberts, Lindi |
| author2 | Hoppe, Heinrich C |
| author_browse | Hoppe, Heinrich C Roberts, Lindi |
| author_facet | Hoppe, Heinrich C Roberts, Lindi |
| author_sort | Roberts, Lindi |
| collection | Thesis |
| description | Includes bibliographical references (leaves 92-109). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3298 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:56.645Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Clinical Pharmacology |
| publisherStr | Division of Clinical Pharmacology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3298 The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells Roberts, Lindi Hoppe, Heinrich C Pharmacology Includes bibliographical references (leaves 92-109). The precise mechanisms of action of the quinoline anti-malarial drugs are uncertain, although they have been found to influence endocytosis, vesicular processing and secretion in malarial parasites and mammalian cells. In this study, the effects of chloroquine, amadiaquine, halofantrine, mefloquine and quinine on the endolysosomal systems in Plasmodium falciparum 3D7, Dictyostelium discoideum and A549 pulmonary cancer cells were examined. 2014-07-28T18:20:16Z 2014-07-28T18:20:16Z 2007 Master Thesis Masters MSc http://hdl.handle.net/11427/3298 eng application/pdf Division of Clinical Pharmacology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Pharmacology Roberts, Lindi The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells |
| thesis_degree_str | Master's |
| title | The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells |
| title_full | The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells |
| title_fullStr | The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells |
| title_full_unstemmed | The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells |
| title_short | The effect of quinoline anti-malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3D7, dictyostelium discoideum and mammalian A549 cells |
| title_sort | effect of quinoline anti malarial drugs on the endolysosomal and secretory pathways of plasmodium falciparum strain 3d7 dictyostelium discoideum and mammalian a549 cells |
| topic | Pharmacology |
| url | http://hdl.handle.net/11427/3298 |
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