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Cryo-electron microscopy of HPV16 pseudovirions reveal changes in capsid conformation upon furin cleavage

Persistent infection by oncogenic human papillomavirus (HPV) is the primary cause of cervical cancer, a leading cause of cancer deaths in women worldwide. There are no treatments for HPV infection, and although prophylactic vaccines are effective and safe, they are HPV type specific, provide little...

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Bibliographic Details
Main Author: Marx, Melissa Lauren
Other Authors: Schafer, Georgia
Format: Thesis
Language:English
Published: Department of Clinical Laboratory Sciences 2021
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