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Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2014
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| _version_ | 1867613648598335488 |
|---|---|
| access_status_str | Open Access |
| author | Khatib, Rodaina Omar |
| author2 | Franz, Thomas |
| author_browse | Franz, Thomas Khatib, Rodaina Omar |
| author_facet | Franz, Thomas Khatib, Rodaina Omar |
| author_sort | Khatib, Rodaina Omar |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3408 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:39:29.638Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3408 Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration Khatib, Rodaina Omar Franz, Thomas Krynauw, Hugo Bezuidenhout, Deon Medicine Includes abstract. Includes bibliographical references. Current replacements for diseased arteries include autologous and artificial grafts. The availability of autologous grafts is limited and artificial grafts tend to fail when applied to small calibre vessels (<;6 mm) due to graft thrombosis and mechanical mismatch between artery and graft. Tissue engineering offers a promising approach to overcome these shortcomings. With porosity as a fundamental prerequisite for tissue ingrowth, several techniques have been introduced for producing porous scaffolds including electro-spinning. This study involved the development and optimisation of electro-spun biodegradable scaffolds for vascular tissue regeneration by tailoring parameters of the electro-spinning process and investigating the change in mechanical and physical properties of the scaffolds associated with hydrolytic in vitro degradation. 2014-07-29T09:04:08Z 2014-07-29T09:04:08Z 2013 Master Thesis Masters MSc http://hdl.handle.net/11427/3408 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Khatib, Rodaina Omar Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration |
| thesis_degree_str | Master's |
| title | Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration |
| title_full | Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration |
| title_fullStr | Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration |
| title_full_unstemmed | Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration |
| title_short | Optimization of structural and mechanical properties of electro-spun biodegradable scaffolds for vascular vissue regeneration |
| title_sort | optimization of structural and mechanical properties of electro spun biodegradable scaffolds for vascular vissue regeneration |
| topic | Medicine |
| url | http://hdl.handle.net/11427/3408 |
| work_keys_str_mv | AT khatibrodainaomar optimizationofstructuralandmechanicalpropertiesofelectrospunbiodegradablescaffoldsforvascularvissueregeneration |