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A study of aminolaevulinic acid synthase

Bibliography: leaves 203-245.

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Bibliographic Details
Main Author: Nahman, Carolyn Joy
Other Authors: Kirsch, Ralph
Format: Thesis
Language:English
Published: Department of Medicine 2014
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access_status_str Open Access
author Nahman, Carolyn Joy
author2 Kirsch, Ralph
author_browse Kirsch, Ralph
Nahman, Carolyn Joy
author_facet Kirsch, Ralph
Nahman, Carolyn Joy
author_sort Nahman, Carolyn Joy
collection Thesis
description Bibliography: leaves 203-245.
format Thesis
id oai:open.uct.ac.za:11427/3439
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:31:34.243Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Department of Medicine
publisherStr Department of Medicine
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/3439 A study of aminolaevulinic acid synthase Nahman, Carolyn Joy Kirsch, Ralph Meissner, Peter Medicine Bibliography: leaves 203-245. Delta-aminolaevulinic acid synthase (ALAS) is the first enzyme in the haem biosynthetic pathway, and in mammals is present in two isoforms - differing in regulation and encoded for on different chromosomes. The hepatic form is up-regulated in states of haem deficiency and thus implicated in the acute attack of porphyria. Given the large number of patients who suffer from an acute form porphyria in South Africa the regulation of the human hepatic form of the enzyme is of considerable interest. 2014-07-29T09:08:47Z 2014-07-29T09:08:47Z 2001 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3439 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Medicine
Nahman, Carolyn Joy
A study of aminolaevulinic acid synthase
thesis_degree_str Doctoral
title A study of aminolaevulinic acid synthase
title_full A study of aminolaevulinic acid synthase
title_fullStr A study of aminolaevulinic acid synthase
title_full_unstemmed A study of aminolaevulinic acid synthase
title_short A study of aminolaevulinic acid synthase
title_sort study of aminolaevulinic acid synthase
topic Medicine
url http://hdl.handle.net/11427/3439
work_keys_str_mv AT nahmancarolynjoy astudyofaminolaevulinicacidsynthase
AT nahmancarolynjoy studyofaminolaevulinicacidsynthase