Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Bibliography: leaves 203-245.
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2014
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613150340186112 |
|---|---|
| access_status_str | Open Access |
| author | Nahman, Carolyn Joy |
| author2 | Kirsch, Ralph |
| author_browse | Kirsch, Ralph Nahman, Carolyn Joy |
| author_facet | Kirsch, Ralph Nahman, Carolyn Joy |
| author_sort | Nahman, Carolyn Joy |
| collection | Thesis |
| description | Bibliography: leaves 203-245. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3439 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:34.243Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3439 A study of aminolaevulinic acid synthase Nahman, Carolyn Joy Kirsch, Ralph Meissner, Peter Medicine Bibliography: leaves 203-245. Delta-aminolaevulinic acid synthase (ALAS) is the first enzyme in the haem biosynthetic pathway, and in mammals is present in two isoforms - differing in regulation and encoded for on different chromosomes. The hepatic form is up-regulated in states of haem deficiency and thus implicated in the acute attack of porphyria. Given the large number of patients who suffer from an acute form porphyria in South Africa the regulation of the human hepatic form of the enzyme is of considerable interest. 2014-07-29T09:08:47Z 2014-07-29T09:08:47Z 2001 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3439 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Nahman, Carolyn Joy A study of aminolaevulinic acid synthase |
| thesis_degree_str | Doctoral |
| title | A study of aminolaevulinic acid synthase |
| title_full | A study of aminolaevulinic acid synthase |
| title_fullStr | A study of aminolaevulinic acid synthase |
| title_full_unstemmed | A study of aminolaevulinic acid synthase |
| title_short | A study of aminolaevulinic acid synthase |
| title_sort | study of aminolaevulinic acid synthase |
| topic | Medicine |
| url | http://hdl.handle.net/11427/3439 |
| work_keys_str_mv | AT nahmancarolynjoy astudyofaminolaevulinicacidsynthase AT nahmancarolynjoy studyofaminolaevulinicacidsynthase |