Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Includes abstract.
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2014
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613162703945728 |
|---|---|
| access_status_str | Open Access |
| author | Nicholson, Lauren |
| author2 | Lecour, Sandrine |
| author_browse | Lecour, Sandrine Nicholson, Lauren |
| author_facet | Lecour, Sandrine Nicholson, Lauren |
| author_sort | Nicholson, Lauren |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3444 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:45.395Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3444 The role of melatonin in peripartum cardiomyopathy Nicholson, Lauren Lecour, Sandrine Sliwa, Karen Medicine Includes abstract. Includes bibliographical references. Peripartum cardiomyopathy (PPCM) is a heart disease of unknown aetiology emerging in previously healthy women towards the end of pregnancy or first postpartum months. Previous studies have suggested that oxidative stress contributes to the pathogenesis of PPCM. Melatonin is a powerful endogenous antioxidant that can limit the damaging effect of oxidative stress. Melatonin levels are known to be altered in sleep disruption, depression and other cardiac diseases. The aim of this study was to determine if melatonin levels are disrupted in women with PPCM compared to healthy patients. We hypothesised that sleep disruption and depression may contribute to a disruption in their melatonin levels. 2014-07-29T09:08:55Z 2014-07-29T09:08:55Z 2013 Master Thesis Masters MSc http://hdl.handle.net/11427/3444 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Nicholson, Lauren The role of melatonin in peripartum cardiomyopathy |
| thesis_degree_str | Master's |
| title | The role of melatonin in peripartum cardiomyopathy |
| title_full | The role of melatonin in peripartum cardiomyopathy |
| title_fullStr | The role of melatonin in peripartum cardiomyopathy |
| title_full_unstemmed | The role of melatonin in peripartum cardiomyopathy |
| title_short | The role of melatonin in peripartum cardiomyopathy |
| title_sort | role of melatonin in peripartum cardiomyopathy |
| topic | Medicine |
| url | http://hdl.handle.net/11427/3444 |
| work_keys_str_mv | AT nicholsonlauren theroleofmelatonininperipartumcardiomyopathy AT nicholsonlauren roleofmelatonininperipartumcardiomyopathy |