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Maternal Haemoglobin and outcome of pregnancy

Background: The association between maternal haemoglobin concentration and the outcome of pregnancy has been a source of continual controversy. Preterm delivery and low birth weight are major causes of stillbirths and early neonatal deaths. Pre-eclampsia is a major complication which occurs during p...

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Main Author: Amponsah, Kwaku Poku
Other Authors: Petro, Gregory
Format: Thesis
Language:English
Published: Department of Obstetrics and Gynaecology 2022
Subjects:
Obstetrics and Gynaecology
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access_status_str Open Access
author Amponsah, Kwaku Poku
author2 Petro, Gregory
author_browse Amponsah, Kwaku Poku
Petro, Gregory
author_facet Petro, Gregory
Amponsah, Kwaku Poku
author_sort Amponsah, Kwaku Poku
collection Thesis
description Background: The association between maternal haemoglobin concentration and the outcome of pregnancy has been a source of continual controversy. Preterm delivery and low birth weight are major causes of stillbirths and early neonatal deaths. Pre-eclampsia is a major complication which occurs during pregnancy and leads to significant maternal and fetal morbidity and mortality. This study aims to assess the association between maternal haemoglobin concentration and pregnancy outcome. Objectives: To assess the association between maternal haemoglobin concentration and pre-eclampsia, preterm birth and low birth weight. Methods: Retrospective analysis of 191 patients who delivered an infant of 28 weeks gestation or more from 1st to 22nd May 2017 at New Somerset Hospital with documented maternal haemoglobin concentration at 22 – 33 weeks gestation. The maternal haemoglobin concentration used was the lowest documented during 22 – 33 weeks gestation. Main outcome measures: Development of pre-eclampsia, low birth weight and preterm birth. Results: The distribution of pre-eclampsia, low birth weight and preterm birth were skewed towards the higher side of the maternal haemoglobin concentration spectrum. There were statistically significant differences in the development of pre-eclampsia, low birth weight and preterm birth between maternal haemoglobin concentrations =>13g/dl and that of < 13g/dl. Pre-eclampsia was associated with relatively lower birth weight, preterm birth and low placental weight independently of the haemoglobin status. Conclusion: High maternal haemoglobin concentration at 22 – 33 weeks gestation is associated with an increased prevalence of pre-eclampsia, low birth weight and preterm birth.
format Thesis
id oai:open.uct.ac.za:11427/36501
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:36:41.339Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher Department of Obstetrics and Gynaecology
publisherStr Department of Obstetrics and Gynaecology
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/36501 Maternal Haemoglobin and outcome of pregnancy Amponsah, Kwaku Poku Petro, Gregory Fakier, Ahminah Obstetrics and Gynaecology Background: The association between maternal haemoglobin concentration and the outcome of pregnancy has been a source of continual controversy. Preterm delivery and low birth weight are major causes of stillbirths and early neonatal deaths. Pre-eclampsia is a major complication which occurs during pregnancy and leads to significant maternal and fetal morbidity and mortality. This study aims to assess the association between maternal haemoglobin concentration and pregnancy outcome. Objectives: To assess the association between maternal haemoglobin concentration and pre-eclampsia, preterm birth and low birth weight. Methods: Retrospective analysis of 191 patients who delivered an infant of 28 weeks gestation or more from 1st to 22nd May 2017 at New Somerset Hospital with documented maternal haemoglobin concentration at 22 – 33 weeks gestation. The maternal haemoglobin concentration used was the lowest documented during 22 – 33 weeks gestation. Main outcome measures: Development of pre-eclampsia, low birth weight and preterm birth. Results: The distribution of pre-eclampsia, low birth weight and preterm birth were skewed towards the higher side of the maternal haemoglobin concentration spectrum. There were statistically significant differences in the development of pre-eclampsia, low birth weight and preterm birth between maternal haemoglobin concentrations =>13g/dl and that of < 13g/dl. Pre-eclampsia was associated with relatively lower birth weight, preterm birth and low placental weight independently of the haemoglobin status. Conclusion: High maternal haemoglobin concentration at 22 – 33 weeks gestation is associated with an increased prevalence of pre-eclampsia, low birth weight and preterm birth. 2022-06-22T13:26:10Z 2022-06-22T13:26:10Z 2022 2022-06-22T12:34:56Z Master Thesis Masters MMed http://hdl.handle.net/11427/36501 eng application/pdf Department of Obstetrics and Gynaecology Faculty of Health Sciences
spellingShingle Obstetrics and Gynaecology
Amponsah, Kwaku Poku
Maternal Haemoglobin and outcome of pregnancy
thesis_degree_str Master's
title Maternal Haemoglobin and outcome of pregnancy
title_full Maternal Haemoglobin and outcome of pregnancy
title_fullStr Maternal Haemoglobin and outcome of pregnancy
title_full_unstemmed Maternal Haemoglobin and outcome of pregnancy
title_short Maternal Haemoglobin and outcome of pregnancy
title_sort maternal haemoglobin and outcome of pregnancy
topic Obstetrics and Gynaecology
url http://hdl.handle.net/11427/36501
work_keys_str_mv AT amponsahkwakupoku maternalhaemoglobinandoutcomeofpregnancy

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