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Comparison of estimates of left ventricular ejection fraction using gated blood imagining
Serial measurement of left ventricular ejection fraction (L VEF) using GBP imaging is an established technique for monitoring L VEF in patients undergoing chemotherapy with cardio-toxic medication and in patients after heart transplants. Oncologists at our institution decide that cardio-toxic chemot...
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| Format: | Thesis |
| Language: | English |
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Division of Nuclear Medicine
2022
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| _version_ | 1867614294888153088 |
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| access_status_str | Open Access |
| author | Steyn,Rachelle |
| author2 | acquisition |
| author_browse | Steyn,Rachelle acquisition |
| author_facet | acquisition Steyn,Rachelle |
| author_sort | Steyn,Rachelle |
| collection | Thesis |
| description | Serial measurement of left ventricular ejection fraction (L VEF) using GBP imaging is an established technique for monitoring L VEF in patients undergoing chemotherapy with cardio-toxic medication and in patients after heart transplants. Oncologists at our institution decide that cardio-toxic chemotherapy should be discontinued if the L VEF decreases by 10%, or if a value of 50% is reached. In patients with baseline L VEFs of less than 50% but greater than 30% therapy will be discontinued if the L VEF decreases by 10% or if a value of less than 30% is reached. This is in accordance with the guidelines set out by the Oxford Textbook ofOncology.3 In patients who have had heart transplants, GBP studies are used to monitor L VEF. If there is a decrease in L VEF, cardiologists may decide to start glucocoricosteroids for rejection. It is therefore imperative that serial studies on an individual patient are comparable. There are two software systems used in our nuclear medicine department; the Siemens system and the Hermes system. In a pilot study we found large differences between the L VEFs calculated by the two systems. This is consistent with the consensus in the literature that different software programs for processing GBP studies cannot be used interchangeably. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/36794 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:49:45.987Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Division of Nuclear Medicine |
| publisherStr | Division of Nuclear Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/36794 Comparison of estimates of left ventricular ejection fraction using gated blood imagining Steyn,Rachelle acquisition cameras comparison gated blood pool studies nuclear medicine Serial measurement of left ventricular ejection fraction (L VEF) using GBP imaging is an established technique for monitoring L VEF in patients undergoing chemotherapy with cardio-toxic medication and in patients after heart transplants. Oncologists at our institution decide that cardio-toxic chemotherapy should be discontinued if the L VEF decreases by 10%, or if a value of 50% is reached. In patients with baseline L VEFs of less than 50% but greater than 30% therapy will be discontinued if the L VEF decreases by 10% or if a value of less than 30% is reached. This is in accordance with the guidelines set out by the Oxford Textbook ofOncology.3 In patients who have had heart transplants, GBP studies are used to monitor L VEF. If there is a decrease in L VEF, cardiologists may decide to start glucocoricosteroids for rejection. It is therefore imperative that serial studies on an individual patient are comparable. There are two software systems used in our nuclear medicine department; the Siemens system and the Hermes system. In a pilot study we found large differences between the L VEFs calculated by the two systems. This is consistent with the consensus in the literature that different software programs for processing GBP studies cannot be used interchangeably. 2022-09-01T08:19:41Z 2022-09-01T08:19:41Z 2013 2022-09-01T08:18:59Z Master Thesis Masters MMed http://hdl.handle.net/11427/36794 eng application/pdf Division of Nuclear Medicine Faculty of Health Sciences |
| spellingShingle | nuclear medicine Steyn,Rachelle Comparison of estimates of left ventricular ejection fraction using gated blood imagining |
| thesis_degree_str | Master's |
| title | Comparison of estimates of left ventricular ejection fraction using gated blood imagining |
| title_full | Comparison of estimates of left ventricular ejection fraction using gated blood imagining |
| title_fullStr | Comparison of estimates of left ventricular ejection fraction using gated blood imagining |
| title_full_unstemmed | Comparison of estimates of left ventricular ejection fraction using gated blood imagining |
| title_short | Comparison of estimates of left ventricular ejection fraction using gated blood imagining |
| title_sort | comparison of estimates of left ventricular ejection fraction using gated blood imagining |
| topic | nuclear medicine |
| url | http://hdl.handle.net/11427/36794 |
| work_keys_str_mv | AT steynrachelle comparisonofestimatesofleftventricularejectionfractionusinggatedbloodimagining |