Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting
Background Accurate weight estimation in emergency centres is important to ensure accurate treatment and limit adverse outcomes. The mid-upper arm circumference (MUAC) as a weight estimation tool has recently expanded to adults. The MUAC's ease of use and cost effectiveness could be beneficial to es...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of General Surgery
2023
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613942191226880 |
|---|---|
| access_status_str | Open Access |
| author | Chen, Emily |
| author2 | Saunders, Colleen |
| author_browse | Chen, Emily Saunders, Colleen |
| author_facet | Saunders, Colleen Chen, Emily |
| author_sort | Chen, Emily |
| collection | Thesis |
| description | Background Accurate weight estimation in emergency centres is important to ensure accurate treatment and limit adverse outcomes. The mid-upper arm circumference (MUAC) as a weight estimation tool has recently expanded to adults. The MUAC's ease of use and cost effectiveness could be beneficial to estimate the weight of sick, adult patients presenting to emergency centres. The objectives were to assess correlation between MUAC and both weight and body mass index (BMI) in adults, externally validate an existing MUAC-based weight estimation formula in a high HIV prevalent emergency centre, and if inaccurate, to derive a MUAC-based weight estimation formula more suitable to the adult study population. Methods A cross-sectional diagnostic study was done in the emergency centre of Khayelitsha hospital, South Africa. Anthropometric data (MUAC, weight and height) and HIV status were obtained from consecutive adult (≥18 year) participants. Correlation of MUAC with weight and BMI were determined using Spearman's correlation coefficient with 95% confidence intervals in all participants and in HIV positive participants. Predicted weights were calculated from previously developed formulae (regression formula: kg=(3.8484×MUAC)−46.8585; simplified formula: kg=(4×MUAC)−50). The agreement between the predicted and observed weights were graphically assessed with a calibration plot. Linear regression was used to derive a MUAC-based formula in the study population. Results A total of 244 participants (median age = 37 years; 111 male) were included, of whom 121 (49.6%) were HIV positive. The correlation between MUAC and weight was 0.93 (HIV positive 0.92), and between MUAC and BMI 0.93 (HIV positive 0.94). The regression formula predicted weight within 10%, 20% and 30% of actual weight in 43.9%, 77.5% and 90.2% of all participants and 33.1%, 69.5% and 85.1% in HIV positive participants. The simplified formula predicted weights within 10%, 20% and 30% of actual weight in 46.7%, 77.5% and 89.8% of all participants and in 35.5%, 70.2% and 85.1% in HIV positive participants. The locally derived formula (kg=(3x MUAC) -16) better estimated weight in the local population. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/37098 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:44:09.630Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Division of General Surgery |
| publisherStr | Division of General Surgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/37098 The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting Chen, Emily Saunders, Colleen van Hoving, Daniël J Medicine Background Accurate weight estimation in emergency centres is important to ensure accurate treatment and limit adverse outcomes. The mid-upper arm circumference (MUAC) as a weight estimation tool has recently expanded to adults. The MUAC's ease of use and cost effectiveness could be beneficial to estimate the weight of sick, adult patients presenting to emergency centres. The objectives were to assess correlation between MUAC and both weight and body mass index (BMI) in adults, externally validate an existing MUAC-based weight estimation formula in a high HIV prevalent emergency centre, and if inaccurate, to derive a MUAC-based weight estimation formula more suitable to the adult study population. Methods A cross-sectional diagnostic study was done in the emergency centre of Khayelitsha hospital, South Africa. Anthropometric data (MUAC, weight and height) and HIV status were obtained from consecutive adult (≥18 year) participants. Correlation of MUAC with weight and BMI were determined using Spearman's correlation coefficient with 95% confidence intervals in all participants and in HIV positive participants. Predicted weights were calculated from previously developed formulae (regression formula: kg=(3.8484×MUAC)−46.8585; simplified formula: kg=(4×MUAC)−50). The agreement between the predicted and observed weights were graphically assessed with a calibration plot. Linear regression was used to derive a MUAC-based formula in the study population. Results A total of 244 participants (median age = 37 years; 111 male) were included, of whom 121 (49.6%) were HIV positive. The correlation between MUAC and weight was 0.93 (HIV positive 0.92), and between MUAC and BMI 0.93 (HIV positive 0.94). The regression formula predicted weight within 10%, 20% and 30% of actual weight in 43.9%, 77.5% and 90.2% of all participants and 33.1%, 69.5% and 85.1% in HIV positive participants. The simplified formula predicted weights within 10%, 20% and 30% of actual weight in 46.7%, 77.5% and 89.8% of all participants and in 35.5%, 70.2% and 85.1% in HIV positive participants. The locally derived formula (kg=(3x MUAC) -16) better estimated weight in the local population. 2023-03-02T07:44:25Z 2023-03-02T07:44:25Z 2022 2023-02-20T12:22:51Z Master Thesis Masters MMed http://hdl.handle.net/11427/37098 eng application/pdf Division of General Surgery Faculty of Health Sciences |
| spellingShingle | Medicine Chen, Emily The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting |
| thesis_degree_str | Master's |
| title | The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting |
| title_full | The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting |
| title_fullStr | The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting |
| title_full_unstemmed | The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting |
| title_short | The validation of the mid-upper arm circumference measurement in adults as a weight estimation tool in a high HIV prevalence setting |
| title_sort | validation of the mid upper arm circumference measurement in adults as a weight estimation tool in a high hiv prevalence setting |
| topic | Medicine |
| url | http://hdl.handle.net/11427/37098 |
| work_keys_str_mv | AT chenemily thevalidationofthemidupperarmcircumferencemeasurementinadultsasaweightestimationtoolinahighhivprevalencesetting AT chenemily validationofthemidupperarmcircumferencemeasurementinadultsasaweightestimationtoolinahighhivprevalencesetting |