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Genetic and pharmacokinetics factors associated with susceptibility to kanamycin induced cochleotoxicity in a cohort of patients undergoing MDR/RR-TB treatment

South Africa is one of the countries with a high incidence of multidrug-resistant tuberculosis (MDR-TB) and rifampicin resistance tuberculosis (RR-TB). The standard MDR/RR-TB regimen prescribed in South Africa, at the time of the present study included Kanamycin, an aminoglycoside with a known cochl...

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Bibliographic Details
Main Author: Ghafari, Nazanin
Other Authors: Ramma, Lebogang
Format: Thesis
Language:English
Published: Department of Health and Rehabilitation Sciences 2023
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