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Identification of a novel HIV-1C protease from a microbial source

HIV-1 subtype C is currently the most prevalent in the epidemiology of HIV/AIDS cases in subSaharan Africa. Most clinical protease inhibitors (PIs) were designed against subtype B and are reported to have reduced activity against subtype C proteases. Our initial hypothesis was to create an Escherich...

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Bibliographic Details
Main Author: Sonday, Zarinah
Other Authors: Blackburn, Jonathan
Format: Thesis
Language:English
Published: Department of Integrative Biomedical Sciences (IBMS) 2023
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