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Comparing mortality calculators for emergency laparotomy in Cape Town
Introduction Emergency laparotomies (EL) are high risk surgeries, a result consistent across multiple national databases and audits. Risk prediction calculators (RPC) were developed to accurately stratify risk of mortality in these emergency patients, often frail prior to surgery. Access to post-ope...
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| Format: | Thesis |
| Language: | English |
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Division of General Surgery
2024
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| _version_ | 1867613255121240064 |
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| access_status_str | Open Access |
| author | Awasthi, Neha |
| author2 | Rayamajhi, Shreya |
| author_browse | Awasthi, Neha Rayamajhi, Shreya |
| author_facet | Rayamajhi, Shreya Awasthi, Neha |
| author_sort | Awasthi, Neha |
| collection | Thesis |
| description | Introduction Emergency laparotomies (EL) are high risk surgeries, a result consistent across multiple national databases and audits. Risk prediction calculators (RPC) were developed to accurately stratify risk of mortality in these emergency patients, often frail prior to surgery. Access to post-operative care including high-care and Intensive Care Unit is limited in LMIC hospitals. Aims and Methods To determine the risk of mortality following surgery using three risk prediction calculators – namely National Emergency Laparotomy Audit's New Risk Prediction Calculator (NELANRPC), Portsmouth Physiological and Operative Society Score (P-POSSUM), and African Surgical Outcomes Study (ASOS) to 215 patients who underwent non-trauma EL in a tertiary level hospital in South Africa. Results Mortality on post-operative day 30 in this cohort was 24.2%. Colorectal resections were most performed and had the highest mortality rate (30.6%). For risk prediction calculators, the NRPC had the largest AUC-ROC (0.86 95% CI, 0.803 to 0.920), followed by P-POSSUM (0.84 95% CI, 0.780 to 0.899), and ASOS (0.806 95% CI, 0.74 to 0.87) having the least. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/39194 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:13.838Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Division of General Surgery |
| publisherStr | Division of General Surgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/39194 Comparing mortality calculators for emergency laparotomy in Cape Town Awasthi, Neha Rayamajhi, Shreya General Surgery Introduction Emergency laparotomies (EL) are high risk surgeries, a result consistent across multiple national databases and audits. Risk prediction calculators (RPC) were developed to accurately stratify risk of mortality in these emergency patients, often frail prior to surgery. Access to post-operative care including high-care and Intensive Care Unit is limited in LMIC hospitals. Aims and Methods To determine the risk of mortality following surgery using three risk prediction calculators – namely National Emergency Laparotomy Audit's New Risk Prediction Calculator (NELANRPC), Portsmouth Physiological and Operative Society Score (P-POSSUM), and African Surgical Outcomes Study (ASOS) to 215 patients who underwent non-trauma EL in a tertiary level hospital in South Africa. Results Mortality on post-operative day 30 in this cohort was 24.2%. Colorectal resections were most performed and had the highest mortality rate (30.6%). For risk prediction calculators, the NRPC had the largest AUC-ROC (0.86 95% CI, 0.803 to 0.920), followed by P-POSSUM (0.84 95% CI, 0.780 to 0.899), and ASOS (0.806 95% CI, 0.74 to 0.87) having the least. 2024-03-08T06:37:25Z 2024-03-08T06:37:25Z 2023 2024-03-08T06:21:00Z Thesis / Dissertation Masters MMed http://hdl.handle.net/11427/39194 eng application/pdf Division of General Surgery Faculty of Health Sciences |
| spellingShingle | General Surgery Awasthi, Neha Comparing mortality calculators for emergency laparotomy in Cape Town |
| thesis_degree_str | Master's |
| title | Comparing mortality calculators for emergency laparotomy in Cape Town |
| title_full | Comparing mortality calculators for emergency laparotomy in Cape Town |
| title_fullStr | Comparing mortality calculators for emergency laparotomy in Cape Town |
| title_full_unstemmed | Comparing mortality calculators for emergency laparotomy in Cape Town |
| title_short | Comparing mortality calculators for emergency laparotomy in Cape Town |
| title_sort | comparing mortality calculators for emergency laparotomy in cape town |
| topic | General Surgery |
| url | http://hdl.handle.net/11427/39194 |
| work_keys_str_mv | AT awasthineha comparingmortalitycalculatorsforemergencylaparotomyincapetown |