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Background: Efavirenz (EFV) is a widely used antiretroviral medication in HIV treatment, primarily metabolized by cytochrome P450 CYP2B6, an enzyme whose loss of function polymorphisms have been associated with risk of EFV neurotoxicity. Patients with late onset efavirenz neurotoxicity syndrome (LEN...
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| Format: | Thesis |
| Language: | English |
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Department of Medicine
2024
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