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Towards designing de novo (1--->4)-linked polysaccharides
Carbohydrates are invaluable in a variety of industrial applications ranging from biodegradable materials to pharmaceutical drug carriers. Small functional groups, such as hydroxyl, amine, N-acetylamide and methoxy are commonly employed for creating de novo saccharides with enhanced functionality. T...
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| Format: | Thesis |
| Language: | English |
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Department of Chemistry
2024
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| _version_ | 1867613297400872960 |
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| access_status_str | Open Access |
| author | Chen, Jeff Yu-Jen |
| author_browse | Chen, Jeff Yu-Jen |
| author_facet | Chen, Jeff Yu-Jen |
| author_sort | Chen, Jeff Yu-Jen |
| collection | Thesis |
| description | Carbohydrates are invaluable in a variety of industrial applications ranging from biodegradable materials to pharmaceutical drug carriers. Small functional groups, such as hydroxyl, amine, N-acetylamide and methoxy are commonly employed for creating de novo saccharides with enhanced functionality. The physiochemical properties of carbohydrates are governed by their conformations and the polarity of their substituents strongly influences the overall flexibility of such biomolecules. In this thesis, two types of (1--->4)-inter-glycosidic interactions, viz. hydrogen bonding and hydrophobic effects, are investigated. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/40104 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:54.099Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/40104 Towards designing de novo (1--->4)-linked polysaccharides Chen, Jeff Yu-Jen Chemistry Carbohydrates are invaluable in a variety of industrial applications ranging from biodegradable materials to pharmaceutical drug carriers. Small functional groups, such as hydroxyl, amine, N-acetylamide and methoxy are commonly employed for creating de novo saccharides with enhanced functionality. The physiochemical properties of carbohydrates are governed by their conformations and the polarity of their substituents strongly influences the overall flexibility of such biomolecules. In this thesis, two types of (1--->4)-inter-glycosidic interactions, viz. hydrogen bonding and hydrophobic effects, are investigated. 2024-07-02T09:27:18Z 2024-07-02T09:27:18Z 2004 2024-07-01T08:44:21Z Thesis / Dissertation Doctoral PhD http://hdl.handle.net/11427/40104 eng application/pdf Department of Chemistry Faculty of Science |
| spellingShingle | Chemistry Chen, Jeff Yu-Jen Towards designing de novo (1--->4)-linked polysaccharides |
| thesis_degree_str | Doctoral |
| title | Towards designing de novo (1--->4)-linked polysaccharides |
| title_full | Towards designing de novo (1--->4)-linked polysaccharides |
| title_fullStr | Towards designing de novo (1--->4)-linked polysaccharides |
| title_full_unstemmed | Towards designing de novo (1--->4)-linked polysaccharides |
| title_short | Towards designing de novo (1--->4)-linked polysaccharides |
| title_sort | towards designing de novo 1 4 linked polysaccharides |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/40104 |
| work_keys_str_mv | AT chenjeffyujen towardsdesigningdenovo14linkedpolysaccharides |